Alginate-based hydrogels mediated biomedical applications: A review

Y Ren, Q Wang, W Xu, M Yang, W Guo, S He… - International Journal of …, 2024 - Elsevier
With the development in the field of biomaterials, research on alternative biocompatible
materials has been initiated, and alginate in polysaccharides has become one of the …

Designing biofunctional hydrogels for stem cell biology and regenerative medicine applications

TTH Thi, M Laney, H Zhang, F Martinez, Y Lee… - Journal of Industrial and …, 2024 - Elsevier
Stem cell therapy has shown remarkable promise for treating various diseases and
disorders. This strategy attenuates disease symptoms and stimulates endogenous and …

Alginate sulfonamide hydrogel beads for 5-fluorouracil delivery: antitumor activity, cytotoxicity assessment, and theoretical investigation

MS Hashem, RA Sobh, AM Fahim… - International Journal of …, 2024 - Elsevier
This study focused on grafting a new monomer (E)-N-(4-(3-(4-bromophenyl) acryloyl)
phenyl)-4-methyl benzene sulfonamide (Br-PS) onto sodium alginate (Alg) using a free …

Facile preparation of a pH-sensitive biocompatible nanocarrier based on magnetic layered double hydroxides/Cu MOFs-chitosan crosslinked к-carrageenan for …

A Taghikhani, M Babazadeh, S Davaran… - Colloids and Surfaces B …, 2024 - Elsevier
Recently, the biocompatibility of hydrogel nanoparticles has gained considerable research
attention in the field of drug delivery. In this regard, we design a pH-controlled nanocarrier …

Size-dependent cellular uptake of sodium alginate passivated tin dioxide nanoparticles in triple-negative breast cancer cells

C Karthikeyan, K Varaprasad, S Kim, AK Jangid… - Journal of Industrial and …, 2023 - Elsevier
The new development of inorganic (IO) nanoparticle (NPs)-based nanomedicines in
anticancer therapy is an active area of research. The cellular uptake of IO NPs plays a …

Exploring the effects of micro-nano surface topography on MG63 osteoblast-like cell responses: An in vitro study

S Jafarkhani, E Amiri, S Moazzeni… - Colloids and Surfaces A …, 2023 - Elsevier
The osseointegration property of dental and bone implants is a crucial factor for proper
healing, and is entirely influenced by the surface characteristics, including surface chemistry …

A comprehensive review of hydrogel-based drug delivery systems: classification, properties, recent trends, and applications

H Hameed, S Faheem, AC Paiva-Santos… - AAPS …, 2024 - Springer
As adaptable biomaterials, hydrogels have shown great promise in several industries, which
include the delivery of drugs, engineering of tissues, biosensing, and regenerative medicine …

Revolutionizing colon cancer therapy by site-specific 5-fluorouracil delivery with novel stimuli-responsive mucoadhesive hydrogel: optimization via response surface …

H Hanan, F Pervaiz, M Ijaz, SM Javaid… - Journal of Drug Delivery …, 2024 - Elsevier
fluorouracil (FU) is the key option of systemic therapy for advanced metastatic colon cancer
but has a cytotoxic impact on normal cells after intravenous administration therefore the …

[HTML][HTML] Hybrid nanocarriers based on polyacrylic acid, polyvinyl pyrrolidone, and molybdenum disulfide for enhanced 5-fluorouracil delivery in lung cancer therapy

M Pourmadadi, M Abdouss, S Mazinani… - Inorganic Chemistry …, 2024 - Elsevier
An innovative hydrogel nanocomposite, synthesized from a hybrid of PAA, PVP, and MoS 2,
represents a pioneering solution for pH-responsive drug delivery. This nanocomposite is …

Tumor microenvironment-responsive 6-mercaptopurine-releasing injectable hydrogel for colon cancer treatment

S Kim, W Lee, H Park, K Kim - Gels, 2023 - mdpi.com
Colon cancer is a significant health concern. The development of effective drug delivery
systems is critical for improving treatment outcomes. In this study, we developed a drug …