Purpose of review This review comprehensively discusses the role of the gut microbiome
and its metabolites in health and disease and sheds light on the importance of a holistic …

Chemotherapy-induced nausea and vomiting (CINV) is a common side effect of patients with
cancer receiving chemotherapeutic drugs. However, the pathological mechanism of CINV is …

Enteric symptoms are hallmarks of prodromal Parkinson's disease (PD) that appear decades
before the onset of motor symptoms and diagnosis. PD patients possess circulating T cells …

Background Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction
frequently accompanied by mental conditions, including depression and anxiety. Despite …

Dopamine (DA) is a catecholamine regulatory molecule with potential role in physiology and
physiopathology of the intestinal tract. Various cellular sources of DA have been indicated …

Ageing is inevitable in all living organisms and is associated with physical deterioration,
disease and eventually death. Dysbiosis, which is the alteration of the gut microbiome …

Background Gastric cancer (GC) is the fifth most common cancer worldwide and the most
commonly diagnosed cancer in Iran. The nervous system provides proximity to tumor cells …

Many studies showed that dopamine receptors (DRs) agonists have anti-inflammatory
effects. Rotigotine, a non-ergot dopamine receptor agonist, mainly actives …

Stress-induced abnormalities in gut monoamine levels (eg, serotonin, dopamine,
norepinephrine) have been linked to gastrointestinal (GI) dysfunction, as well as the …

Dopamine (DA) is a neurotransmitter synthesized in the human body that acts on multiple
organs throughout the body, reaching them through the blood circulation. Neurotransmitters …