High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities

P Müller, J de la Cuesta-Zuluaga, M Kuhn… - Nature …, 2024 - nature.com
The human gut microbiome is a key contributor to health, and its perturbations are linked to
many diseases. Small-molecule xenobiotics such as drugs, chemical pollutants and food …

Microbial transformation of dietary xenobiotics shapes gut microbiome composition

EJ Culp, NT Nelson, AA Verdegaal, AL Goodman - Cell, 2024 - cell.com
Diet is a major determinant of gut microbiome composition, and variation in diet-microbiome
interactions may contribute to variation in their health consequences. To mechanistically …

Targeted remodeling of the human gut microbiome using Juemingzi (Senna seed extracts)

AB Narrowe, JMS Lemons, KK Mahalak… - Frontiers in Cellular …, 2024 - frontiersin.org
The genus Senna contains globally distributed plant species of which the leaves, roots, and
seeds have multiple traditional medicinal and nutritional uses. Notable chemical compounds …