Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

Tissue-derived decellularized biomaterials are ideal for tissue engineering applications as
they mimic the biochemical composition of the native tissue. These materials can be used as …

The corneal stroma plays several pivotal roles within the eye. Optically, it is the main
refracting lens and thus has to combine almost perfect transmission of visible light with …

No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

The cornea consists primarily of three layers: an outer layer containing an epithelium, a
middle stromal layer consisting of a collagen-rich extracellular matrix (ECM) interspersed …

Small leucine‐rich proteoglycans (SLRP s) are involved in a variety of biological and
pathological processes. This review focuses on their regulatory roles in matrix assembly …

The small leucine-rich proteoglycans (SLRPs), decorin and biglycan, are key regulators of
collagen fibril and matrix assembly. The goal of this work was to elucidate the roles of …

Small leucine-rich proteoglycans/proteins (SLRPs) are associated with collagen fibril
formation, and therefore important for the proper formation of extracellular matrices. SLRPs …