Rifampicin drug resistance and host immunity in tuberculosis: more than meets the eye

S Bobba, SA Khader - Trends in immunology, 2023 - cell.com
Tuberculosis (TB) is the leading cause of death due to an infectious agent, with more than
1.5 million deaths attributed to TB annually worldwide. The global dissemination of drug …

Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects

K Ochi - The Journal of antibiotics, 2017 - nature.com
As bacteria and fungi have been found to contain genes encoding enzymes that synthesize
a plethora of potential secondary metabolites, interest has grown in the activation of these …

Global spread of three multidrug-resistant lineages of Staphylococcus epidermidis

JYH Lee, IR Monk, A Gonçalves da Silva… - Nature …, 2018 - nature.com
Staphylococcus epidermidis is a conspicuous member of the human microbiome, widely
present on healthy skin. Here we show that S. epidermidis has also evolved to become a …

Enhanced bacterial adhesion force by rifampicin resistance promotes microbial colonization on PE plastic compared to non-resistant biofilm formation

J Wu, C Liu, R Wang, S Yan, B Chen, X Zhu - Water Research, 2023 - Elsevier
The microbial biofilm formed on plastics, is ubiquitous in the environment. However, the
effects of antibiotic resistance on the development of the biofilm on plastics, especially with …

[HTML][HTML] Concentration-regulated multi-color fluorescent carbon dots for the detection of rifampicin, morin and Al3+

X Tang, Y Zhao, H Yu, S Cui, H Temple… - Materials Today …, 2023 - Elsevier
Carbon dots have many new and interesting phenomena, and the concentration dependent
luminescence wavelength is an intriguing one. Herein, nitrogen-sulfur co-doped carbon dots …

Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria

N Zhu, C Zhong, T Liu, Y Zhu, S Gou, H Bao… - European Journal of …, 2021 - Elsevier
The increasing prevalence of antibiotic resistance in Gram-negative bacteria calls for the
discovery of novel effective therapeutic strategies urgently. Mastoparan-C (MP-C), a typical …

Importance of twitching and surface-associated motility in the virulence of Acinetobacter baumannii

J Corral, M Pérez-Varela, M Sánchez-Osuna, P Cortés… - Virulence, 2021 - Taylor & Francis
Acinetobacter baumannii is a pathogen of increasing clinical importance worldwide,
especially given its ability to readily acquire resistance determinants. Motile strains of this …

Cross-feeding modulates the rate and mechanism of antibiotic resistance evolution in a model microbial community of Escherichia coli and Salmonella enterica

EM Adamowicz, M Muza, JM Chacón… - PLoS …, 2020 - journals.plos.org
With antibiotic resistance rates on the rise, it is critical to understand how microbial species
interactions influence the evolution of resistance. In obligate mutualisms, the survival of any …

Antibiotic Susceptibility Profiles of Dairy Leuconostoc, Analysis of the Genetic Basis of Atypical Resistances and Transfer of Genes In Vitro and in a Food Matrix

AB Flórez, I Campedelli, S Delgado, A Alegria… - PLoS …, 2016 - journals.plos.org
In spite of a global concern on the transfer of antibiotic resistances (AR) via the food chain,
limited information exists on this issue in species of Leuconostoc and Weissella, adjunct …

Colistin resistance in Escherichia coli confers protection of the cytoplasmic but not outer membrane from the polymyxin antibiotic

M Humphrey, GJ Larrouy-Maumus… - …, 2021 - microbiologyresearch.org
Colistin is a polymyxin antibiotic of last resort for the treatment of infections caused by multi-
drug-resistant Gram-negative bacteria. By targeting lipopolysaccharide (LPS), the antibiotic …