Prospect of stem cells in bone tissue engineering: a review

AM Yousefi, PF James, R Akbarzadeh… - Stem cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been the subject of many studies in recent years,
ranging from basic science that looks into MSCs properties to studies that aim for developing …

Ceramic composites as matrices and scaffolds for drug delivery in tissue engineering

W Habraken, JGC Wolke, JA Jansen - Advanced drug delivery reviews, 2007 - Elsevier
Ceramic composites and scaffolds are popular implant materials in the field of dentistry,
orthopedics and plastic surgery. For bone tissue engineering especially CaP-ceramics or …

Differentiation of fetal osteoblasts and formation of mineralized bone nodules by 45S5 Bioglass® conditioned medium in the absence of osteogenic supplements

O Tsigkou, JR Jones, JM Polak, MM Stevens - Biomaterials, 2009 - Elsevier
Bioactive glasses bond strongly to bone in vivo and their ionic dissolution products have
previously been shown to have stimulatory properties on adult and fetal osteoblasts and to …

From natural bone grafts to tissue engineering therapeutics: brainstorming on pharmaceutical formulative requirements and challenges

B Baroli - Journal of pharmaceutical sciences, 2009 - Elsevier
Tissue engineering is an emerging multidisciplinary field of investigation focused on the
regeneration of diseased or injured tissues through the delivery of appropriate molecular …

[HTML][HTML] Multiscale analyses reveal native-like lamellar bone repair and near perfect bone-contact with porous strontium-loaded bioactive glass

H Autefage, F Allen, HM Tang, C Kallepitis… - Biomaterials, 2019 - Elsevier
The efficient healing of critical-sized bone defects using synthetic biomaterial-based
strategies is promising but remains challenging as it requires the development of …

Recommendations and considerations for the use of biologics in orthopedic surgery

S Zwingenberger, C Nich, RD Valladares, Z Yao… - BioDrugs, 2012 - Springer
Reconstruction of extensive bone defects remains technically challenging and has
considerable medical and financial impact on our society. Surgical procedures often require …

Compositional effects on the formation of a calcium phosphate layer and the response of osteoblast-like cells on polymer-bioactive glass composites

HH Lu, A Tang, SC Oh, JP Spalazzi, K Dionisio - Biomaterials, 2005 - Elsevier
Biodegradable polymer-ceramic composites are attractive systems for bone tissue
engineering applications. These composites have the combined advantages of the …

Type I collagen production by osteoblast‐like cells cultured in contact with different bioactive glasses

M Bosetti, L Zanardi, L Hench… - Journal of Biomedical …, 2003 - Wiley Online Library
Bioactive glasses are silica‐based, surface‐active bone substitutes that have shown good
biocompatibility both in bone and in soft tissue and are used in oral and maxillofacial bone …

Macroporous bioactive glass-ceramic scaffolds for tissue engineering

CV Brovarone, E Verné, P Appendino - Journal of Materials Science …, 2006 - Springer
Highly bioactive scaffolds for tissue engineering were synthesized using a glass belonging
to the SiO 2-CaO-K 2 O (SCK) system. The glass SCK was prepared by a traditional melting …

Proliferation and differentiation rates of a human osteoblast‐like cell line (SaOS‐2) in contact with different bone substitute materials

U Mayr‐Wohlfart, J Fiedler, KP Günther… - … Research: An Official …, 2001 - Wiley Online Library
The aim of our study was to investigate the influence of four bone substitutes on the growth
behavior of a human osteoblast‐like cell line (SaOS‐2) culture: pure alpha tricalcium …