Role of microRNAs in breast cancer

R Singh, YY Mo - Cancer biology & therapy, 2013 - Taylor & Francis
MicroRNAs (miRNAs) are a class of post-transcriptional gene regulators with critical
functions in normal cellular processes as well as disease processes. They are small …

MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells

P Ceppi, ME Peter - Oncogene, 2014 - nature.com
Abstract Concepts and experimental models derived from basic research have been
successfully applied to the field of molecular oncology, tremendously increasing our …

Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells

R Sun, S Shen, YJ Zhang, CF Xu, ZT Cao, LP Wen… - Biomaterials, 2016 - Elsevier
Cancer stem cells (CSCs) have garnered increasin g attention over the past decade, as they
are believed to play a crucial role in tumor initiation, progression and metastasis, relapse …

miRNA profiling in pancreatic cancer and restoration of chemosensitivity

S Singh, D Chitkara, V Kumar, SW Behrman, RI Mahato - Cancer letters, 2013 - Elsevier
Pancreatic cancers relapse due to small but distinct population of cancer stem cells (CSCs)
which are in turn regulated by miRNAs. The present study identifies a series of miRNAs …

MicroRNA control of epithelial‐mesenchymal transition in cancer stem cells

J Hao, Y Zhang, M Deng, R Ye, S Zhao… - … journal of cancer, 2014 - Wiley Online Library
Cancer stem cells (CSCs) represent a small subset of cancer cell populations that possess
characteristics associated with normal stem cells. They have the ability to self‐renew, and …

MicroRNA 'signature'during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention

R Munagala, F Aqil, MV Vadhanam, RC Gupta - Cancer letters, 2013 - Elsevier
Dysregulated miRNA expression has been associated with the development and
progression of cancers, including breast cancer. The role of estrogen (E 2) in regulation of …

The role of miRNAs in cancer: from pathogenesis to therapeutic implications

M Seven, OF Karatas, MB Duz, M Ozen - Future oncology, 2014 - Taylor & Francis
Cancer is still one of the dominating causes of deaths worldwide, although there have been
important enhancements for detection and diagnosis of cancer recently. miRNAs are shown …

A miRNA signature of chemoresistant mesenchymal phenotype identifies novel molecular targets associated with advanced pancreatic cancer

A Bera, K VenkataSubbaRao, MS Manoharan, P Hill… - PloS one, 2014 - journals.plos.org
In this study a microRNA (miRNA) signature was identified in a gemcitabine resistant
pancreatic ductal adenocarcinoma (PDAC) cell line model (BxPC3-GZR) and this signature …

Emerging role of microRNAs in cancer and cancer stem cells

J Hao, S Zhao, Y Zhang, Z Zhao, R Ye… - Journal of Cellular …, 2014 - Wiley Online Library
Cancer stem cells (CSCs), or cancer cells with stem cell properties, represent a small
fraction of tumor bulk and are thought to be responsible for tumor formation and metastasis …

Graphene Quantum Dots Eradicate Resistant and Metastatic Cancer Cells by Enhanced Interfacial Inhibition

Y Su, K Ye, J Hu, Z Zhang, Y Wang… - Advanced …, 2024 - Wiley Online Library
Drug‐resistant and metastatic cancer cells such as a small population of cancer stem cells
(CSCs) play a crucial role in metastasis and relapse. Conventional small‐molecule …