Growth and neurodevelopment of HIV-exposed uninfected children: a conceptual framework
CJ Wedderburn, C Evans, S Yeung, DM Gibb… - Current HIV/AIDS …, 2019 - Springer
Abstract Purpose of Review The population of HIV-exposed uninfected (HEU) children is
expanding rapidly, and over one million HEU infants are born each year globally. Several …
expanding rapidly, and over one million HEU infants are born each year globally. Several …
Evaluating neurodevelopmental consequences of perinatal exposure to antiretroviral drugs: current challenges and new approaches
As antiretroviral therapy (ART) becomes increasingly affordable and accessible to women of
childbearing age across the globe, the number of children who are exposed to Human …
childbearing age across the globe, the number of children who are exposed to Human …
Neurodevelopment of breastfed HIV-exposed uninfected and HIV-unexposed children in South Africa
Objectives: To assess neurodevelopment of breastfed HIV-exposed uninfected (HEU) and
breastfed HIV-unexposed children in the context of universal maternal antiretroviral therapy …
breastfed HIV-unexposed children in the context of universal maternal antiretroviral therapy …
Early structural brain development in infants exposed to HIV and antiretroviral therapy in utero in a South African birth cohort
Introduction: There is a growing population of children who are HIV-exposed and uninfected
(HEU) with the successful expansion of antiretroviral therapy (ART) use in pregnancy …
(HEU) with the successful expansion of antiretroviral therapy (ART) use in pregnancy …
Early child development in children who are HIV‐exposed uninfected compared to children who are HIV‐unexposed: observational sub‐study of a cluster‐randomized …
Introduction Exposure to maternal HIV may affect early child development (ECD), although
previous studies have reported heterogeneous findings. We evaluated ECD among children …
previous studies have reported heterogeneous findings. We evaluated ECD among children …
Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques
J Raper, Z Kovacs-Balint, M Mavigner… - Nature …, 2020 - nature.com
Zika virus (ZIKV) infection has a profound impact on the fetal nervous system. The postnatal
period is also a time of rapid brain growth, and it is important to understand the potential …
period is also a time of rapid brain growth, and it is important to understand the potential …
Maternal ART throughout gestation prevents caudate volume reductions in neonates who are HIV exposed but uninfected
Introduction Successful programmes for prevention of vertical HIV transmission have
reduced the risk of infant HIV infection in South Africa from 8% in 2008 to below 1% in …
reduced the risk of infant HIV infection in South Africa from 8% in 2008 to below 1% in …
A neurometabolic pattern of elevated myo-inositol in children who are HIV-exposed and uninfected: A South African birth cohort study
C Bertran-Cobo, CJ Wedderburn… - Frontiers in …, 2022 - frontiersin.org
Introduction Exposure to maternal HIV in pregnancy may be a risk factor for impaired child
neurodevelopment during the first years of life. Altered neurometabolites have been …
neurodevelopment during the first years of life. Altered neurometabolites have been …
Neuroanatomical changes underlying vertical HIV infection in adolescents
X Yu, L Gao, H Wang, Z Yin, J Fang, J Chen… - Frontiers in …, 2019 - frontiersin.org
Purpose: The aim of this study was to investigate how human immunodeficiency virus (HIV)
affects brain development in adolescents, what are susceptible brain regions, and how …
affects brain development in adolescents, what are susceptible brain regions, and how …
In utero exposure to HIV and/or antiretroviral therapy: a systematic review of preclinical and clinical evidence of cognitive outcomes
MS McHenry, KA Balogun… - Journal of the …, 2019 - Wiley Online Library
Introduction With the increasing number of children exposed to HIV or antiretroviral therapy
in utero, there are concerns that this population may have worse neurodevelopmental …
in utero, there are concerns that this population may have worse neurodevelopmental …