The role of minerals in the optimal functioning of the immune system
Minerals fulfil a wide variety of functions in the optimal functioning of the immune system.
This review reports on the minerals that are essential for the immune system's function and …
This review reports on the minerals that are essential for the immune system's function and …
[HTML][HTML] Magnesium in aging, health and diseases
Several changes of magnesium (Mg) metabolism have been reported with aging, including
diminished Mg intake, impaired intestinal Mg absorption and renal Mg wasting. Mild Mg …
diminished Mg intake, impaired intestinal Mg absorption and renal Mg wasting. Mild Mg …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
Calcium signalling in T cells
M Trebak, JP Kinet - Nature Reviews Immunology, 2019 - nature.com
Abstract Calcium (Ca2+) signalling is of paramount importance to immunity. Regulated
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …
Regulation of the germinal center response
M Stebegg, SD Kumar, A Silva-Cayetano… - Frontiers in …, 2018 - frontiersin.org
The germinal center (GC) is a specialized microstructure that forms in secondary lymphoid
tissues, producing long-lived antibody secreting plasma cells and memory B cells, which …
tissues, producing long-lived antibody secreting plasma cells and memory B cells, which …
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats
Y Zhang, J Xu, YC Ruan, MK Yu, M O'Laughlin… - Nature medicine, 2016 - nature.com
Orthopedic implants containing biodegradable magnesium have been used for fracture
repair with considerable efficacy; however, the underlying mechanisms by which these …
repair with considerable efficacy; however, the underlying mechanisms by which these …
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
Activated T cells engage aerobic glycolysis and anabolic metabolism for growth,
proliferation, and effector functions. We propose that a glucose-poor tumor …
proliferation, and effector functions. We propose that a glucose-poor tumor …
[HTML][HTML] Magnesium in man: implications for health and disease
JHF De Baaij, JGJ Hoenderop… - Physiological …, 2015 - journals.physiology.org
Abstract Magnesium (Mg 2+) is an essential ion to the human body, playing an instrumental
role in supporting and sustaining health and life. As the second most abundant intracellular …
role in supporting and sustaining health and life. As the second most abundant intracellular …
The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum
Stimulator of interferon genes (STING) is an endoplasmic reticulum (ER) signaling adaptor
that is essential for the type I interferon response to DNA pathogens. Aberrant activation of …
that is essential for the type I interferon response to DNA pathogens. Aberrant activation of …
NLRP3 inflammasome in neurological diseases, from functions to therapies
L Song, L Pei, S Yao, Y Wu, Y Shang - Frontiers in cellular …, 2017 - frontiersin.org
Neuroinflammation has been identified as a causative factor of multiple neurological
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …
diseases. The nucleotide-binding oligomerization domain-, leucine-rich repeat-and pyrin …