Stem cell therapy for spinal cord injury
L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …
Myelin damage and repair in pathologic CNS: challenges and prospects
A Alizadeh, SM Dyck… - Frontiers in molecular …, 2015 - frontiersin.org
Injury to the central nervous system (CNS) results in oligodendrocyte cell death and
progressive demyelination. Demyelinated axons undergo considerable physiological …
progressive demyelination. Demyelinated axons undergo considerable physiological …
A review of functional electrical stimulation treatment in spinal cord injury
Functional electrical stimulation (FES) has been widely adopted to elicit muscle contraction
in rehabilitation training after spinal cord injury (SCI). Conventional FES modalities include …
in rehabilitation training after spinal cord injury (SCI). Conventional FES modalities include …
Human pluripotent stem cells-based therapies for neurodegenerative diseases: current status and challenges
E Ford, J Pearlman, T Ruan, J Manion, M Waller… - Cells, 2020 - mdpi.com
Neurodegenerative diseases are characterized by irreversible cell damage, loss of neuronal
cells and limited regeneration potential of the adult nervous system. Pluripotent stem cells …
cells and limited regeneration potential of the adult nervous system. Pluripotent stem cells …
The role of current techniques and concepts in peripheral nerve repair
KS Houschyar, A Momeni, MN Pyles… - Plastic surgery …, 2016 - Wiley Online Library
Patients with peripheral nerve injuries, especially severe injury, often face poor nerve
regeneration and incomplete functional recovery, even after surgical nerve repair. This …
regeneration and incomplete functional recovery, even after surgical nerve repair. This …
Oligodendrocyte precursor cells in spinal cord injury: a review and update
N Li, GKK Leung - BioMed research international, 2015 - Wiley Online Library
Spinal cord injury (SCI) is a devastating condition to individuals, families, and society.
Oligodendrocyte loss and demyelination contribute as major pathological processes of …
Oligodendrocyte loss and demyelination contribute as major pathological processes of …
Biomimetic hydrogels direct spinal progenitor cell differentiation and promote functional recovery after spinal cord injury
SA Geissler, AL Sabin, RR Besser… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Demyelination that results from disease or traumatic injury, such as spinal cord
injury (SCI), can have a devastating effect on neural function and recovery. Many …
injury (SCI), can have a devastating effect on neural function and recovery. Many …
Cell reprogramming for oligodendrocytes: A review of protocols and their applications to disease modeling and cell‐based remyelination therapies
A McCaughey‐Chapman… - Journal of Neuroscience …, 2023 - Wiley Online Library
Oligodendrocytes are a type of glial cells that produce a lipid‐rich membrane called myelin.
Myelin assembles into a sheath and lines neuronal axons in the brain and spinal cord to …
Myelin assembles into a sheath and lines neuronal axons in the brain and spinal cord to …
Repeated injections of human umbilical cord blood-derived mesenchymal stem cells significantly promotes functional recovery in rabbits with spinal cord injury of two …
C Yang, G Wang, F Ma, B Yu, F Chen, J Yang… - Stem cell research & …, 2018 - Springer
Abstract Background Spinal cord injuries (SCIs) are sustained by an increasing number of
patients each year worldwide. The treatment of SCIs has long been a hard nut to crack for …
patients each year worldwide. The treatment of SCIs has long been a hard nut to crack for …
Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors
Induced pluripotent stem (iPS) cells are at the forefront of research in regenerative medicine
and are envisaged as a source for personalized tissue repair and cell replacement therapy …
and are envisaged as a source for personalized tissue repair and cell replacement therapy …