HIV infection
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …
virus (HIV), and there are now approximately 37 million individuals living with the infection …
Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies
SP Fuchs, RC Desrosiers - Molecular Therapy Methods & Clinical …, 2016 - cell.com
Attempts to elicit antibodies with potent neutralizing activity against a broad range of human
immunodeficiency virus (HIV) isolates have so far proven unsuccessful. Long-term delivery …
immunodeficiency virus (HIV) isolates have so far proven unsuccessful. Long-term delivery …
Risk of drug resistance among persons acquiring HIV within a randomized clinical trial of single-or dual-agent preexposure prophylaxis
Abstract Background. Preexposure prophylaxis (PrEP) with emtricitabine plus tenofovir
disoproxil fumarate (FTC/TDF) or TDF alone reduces the risk of human immunodeficiency …
disoproxil fumarate (FTC/TDF) or TDF alone reduces the risk of human immunodeficiency …
Understanding protection from SARS-CoV-2 by studying reinfection
J Overbaugh - Nature Medicine, 2020 - nature.com
Understanding protection from SARS-CoV-2 by studying reinfection | Nature Medicine Skip to
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Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women
A reservoir of HIV-infected cells that persists despite suppressive antiretroviral therapy (ART)
is the source of viral rebound upon ART cessation and the major barrier to a cure …
is the source of viral rebound upon ART cessation and the major barrier to a cure …
CD4/CD8 ratio and the risk of Kaposi sarcoma or non-Hodgkin lymphoma in the context of efficiently treated human immunodeficiency virus (HIV) infection: a …
F Caby, M Guiguet, L Weiss, A Winston… - Clinical Infectious …, 2021 - academic.oup.com
Background A persistently low CD4/CD8 ratio has been reported to inversely correlate with
the risk of non-AIDS defining cancer in people living with human immunodeficiency virus …
the risk of non-AIDS defining cancer in people living with human immunodeficiency virus …
Randomized trial of periodic presumptive treatment with high-dose intravaginal metronidazole and miconazole to prevent vaginal infections in HIV-negative women
RS McClelland, JE Balkus, J Lee… - The Journal of …, 2015 - academic.oup.com
Background. Vaginal infections are common, frequently recur, and may increase women's
risk for sexually transmitted infections (STIs). We tested the efficacy of a novel regimen to …
risk for sexually transmitted infections (STIs). We tested the efficacy of a novel regimen to …
Chikungunya virus superinfection exclusion is mediated by a block in viral replication and does not rely on non-structural protein 2
J Boussier, L Levi, J Weger-Lucarelli, EZ Poirier… - PLoS …, 2020 - journals.plos.org
Superinfection exclusion (SIE) is a process by which a virally infected cell is protected from
subsequent infection by the same or a closely related virus. By preventing cell coinfection …
subsequent infection by the same or a closely related virus. By preventing cell coinfection …
Preexposure prophylaxis-selected drug resistance decays rapidly after drug cessation
Objective: Resistance to emtricitabine plus tenofovir disoproxil fumarate (FTC/TDF) or TDF
alone used as preexposure prophylaxis (PrEP) has been detected in individuals who …
alone used as preexposure prophylaxis (PrEP) has been detected in individuals who …
The broad neutralizing antibody responses after HIV-1 superinfection are not dominated by antibodies directed to epitopes common in single infection
V Cortez, B Wang, A Dingens, MM Chen… - PLoS …, 2015 - journals.plos.org
HIV-1 vaccines designed to date have failed to elicit neutralizing antibodies (Nabs) that are
capable of protecting against globally diverse HIV-1 subtypes. One relevant setting to study …
capable of protecting against globally diverse HIV-1 subtypes. One relevant setting to study …