Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by defects in
any of the five subunits of the NADPH oxidase complex responsible for the respiratory burst …

Chronic granulomatous disease (CGD) was first described in 1954 1 and 1957 2 as
recurrent infections occurring in the setting of hypergammaglobulinemia, as opposed to the …

Background. Chronic granulomatous disease (CGD) is due to defective nicotinamide
adenine dinucleotide phosphate oxidase activity and characterized by recurrent infections …

Background Failure to generate phagocyte-derived superoxide and related reactive oxygen
intermediates (ROIs) is the major defect in chronic granulomatous disease, causing …

Chronic granulomatous disease (CGD) was first described in the 1950s and has become a
paradigm for genetic neutrophil diseases. It is characterized by recurrent infections with a …

Gastrointestinal disorders such as chronic or acute diarrhea, malabsorption, abdominal
pain, and inflammatory bowel diseases can indicate immune deficiency. The gastrointestinal …

Chronic granulomatous disease (CGD) still causes significant morbidity and mortality. The
difficulty in considering high-risk yet curative treatments, such as allogeneic bone marrow …

Abstract Chronic Granulomatous Disease is the most commonly encountered
immunodeficiency involving the phagocyte, and is characterized by repeated infections with …

Background Idiopathic noncirrhotic portal hypertension (INCPH) is a rare disease in the W
estern world. As a result, little is known about the clinical characteristics and outcome of …

Cystic fibrosis (CF) liver disease (CFLD), a leading cause of death in CF, is mostly described
in pediatric populations. Adult‐onset CFLD lacks sufficient characterization and diagnostic …