To understand how the microvasculature grows and remodels, researchers require
reproducible systems that emulate the function of living tissue. Innovative contributions …

To improve understanding of microvascular O2 transport, theoretical modeling has been
pursued for many years. The large number of studies in this area attests to the complexities …

The cortical angioarchitecture is a key factor in controlling cerebral blood flow and oxygen
metabolism. Difficulties in imaging the complex microanatomy of the cortex have so far …

Uncovering principles that regulate energy metabolism in the brain requires mapping of
partial pressure of oxygen (PO2) and blood flow with high spatial and temporal resolution …

CHEMICAL BIOPHYSICS QUANTITATIVE ANALYSIS OF CELLULAR SYSTEMS Page 1 102
DANIEL A. BEARD, HONG QIAN CHEMICAL BIOPHYSICS QUANTITATIVE ANALYSIS OF …

At its most fundamental level, cerebral blood flow (CBF) may be modeled as fluid flow driven
through a network of resistors by pressure gradients. The composition of the blood as well …

Background The function and viability of cultured, transplanted, or encapsulated pancreatic
islets is often limited by hypoxia because these islets have lost their vasculature during the …

Objective Cells require energy to carry out their functions and they typically use oxidative
phosphorylation to generate the needed ATP. Thus, cells have a continuous need for …

This article aims to promote integration of angiogenesis-related models, both integration of
the work described herein and many other existing and future models. Integration of …

Objective Oxygen tension in the brain is controlled by the microcirculatory supply of RBC,
but the effect of non‐Newtonian blood flow rheology on tissue oxygenation is not well …