Idiosyncratic drug reactions (IDRs) range from relatively common, mild reactions to rarer,
potentially life-threatening adverse effects that pose significant risks to both human health …

Atypical antipsychotics (AAP) or second-generation antipsychotics are the clinical option for
schizophrenia treatment during acute psychoses, but they are also indicated for …

Background and aim Available evidence suggests elevated serum prolactin (PRL) levels in
olanzapine (OLZ)-treated patients with schizophrenia. However, machine learning (ML) …

High prolactin (PRL) concentration has been shown to induce the apoptosis of ovine ovarian
granulosa cells (GCs), but the underlying mechanisms are unclear. This study aimed to …

Abstract Aim Typical antipsychotics (TAPs) are commonly used to treat schizophrenia and
bipolar disorder. However, extrapyramidal disorders, hyperprolactinemia, and reproductive …

Stress as it relates to infertility has become a global issue attracting public health concern.
The present study examined the morphological changes in ovarian histology in response to …

Hepatitis C virus (HCV) infection is a major health problem worldwide and its eradication is
mandatory. Direct acting HCV polymerase inhibitors, such as Sofosbuvir (SOF), is an …

Mitochondria are potential targets responsible for some drug-and xenobiotic-induced organ
toxicities. However, molecular mechanisms of drug-induced mitochondrial toxicities are …

The present study was aimed to explore the cardio-, immuno-, and nephrotoxic effects of the
antipsychotic agent clozapine (CLZ) and the alleviative potency of sulpiride (SPD) on these …

Purpose: We aimed to investigate the antioxidant activity of nebivolol against possible
damage to the ovarian tissue due to the application of deltamethrin as a toxic agent, by …