Regulatory T cells (Tregs) are important for the induction and maintenance of peripheral
tolerance therefore, they are key in preventing excessive immune responses and …

L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that
is expressed on most circulating leukocytes. Since its identification in 1983, L-selectin has …

Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

Regulatory T (Treg) cells underlie multiple autoimmune disorders and potentialize an anti-
inflammation treatment with adoptive cell therapy. However, systemic delivery of cellular …

Transplantation is unusual in that T cells can recognize alloantigen by at least two distinct
pathways: as intact MHC alloantigen on the surface of donor cells via the direct pathway; …

Promoting immune tolerance to transplanted organs can minimize the amount of
immunosuppressive drugs that patients need to take, reducing lifetime risks of mortality and …

Regulatory T cells (Treg) are well-known for their immune regulatory potential and are
essential for maintaining immune homeostasis. The rationale of Treg-based immunotherapy …

Regulatory T cells (Treg) are a subpopulation of T cells that maintain tolerance to self and
limit other immune responses. They achieve this through different mechanisms including the …

Mesenchymal stem cells (MSCs) have fueled ample translation for the treatment of immune‐
mediated diseases. They exert immunoregulatory and tissue‐restoring effects. MSC …

The mammalian intestine harbors a remarkable number of microbes and their components
and metabolites, which are fundamental for the instigation and development of the host …