Legumain (LGMN) has been demonstrated to be overexpressed not just in breast, prostatic,
and liver tumor cells, but also in the macrophages that compose the tumor …

Highlights•NK cells and unconventional T cells are robustly activated in SARS-CoV-2
infection.•Both populations of cells also home to lung tissue during acute infection.•Severe …

Spectral flow cytometry is an upcoming technique that allows for extensive multicolor panels,
enabling simultaneous investigation of a large number of cellular parameters in a single …

MAIT cells are one representative of a group of related unconventional or pre-set T cells,
and are particularly abundant in humans. While these unconventional T cell types, which …

Targeting T cell malignancies with universal CD7-targeting chimeric antigen receptor T cells
(UCART7) can lead to profound immune deficiency due to loss of normal T and NK cells …

Epidemiological studies have revealed sex differences in the incidence and morbidity of
respiratory virus infection in the human population, and often these observations are …

Prolonged T cell lymphopenia is common in COVID-19, caused by SARS-CoV-2. While the
mechanisms of lymphopenia during COVID-19 remain elusive, it is especially pronounced in …

SARS-CoV-2 is the causative agent of COVID-19 in humans and has resulted in the death of
millions of people worldwide. Similar numbers of infections have been documented in males …

Mucosal associated invariant T (MAIT) cells were first identified as specific for bacterial,
mycobacterial, and fungal organisms, which detect microbially-derived biosynthetic ligands …

Background The global pandemic of coronavirus disease 2019 (COVID‐19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has swept through every …