Computational models in cardiology
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
[HTML][HTML] Techniques for automated local activation time annotation and conduction velocity estimation in cardiac mapping
Measurements of cardiac conduction velocity provide valuable functional and structural
insight into the initiation and perpetuation of cardiac arrhythmias, in both a clinical and …
insight into the initiation and perpetuation of cardiac arrhythmias, in both a clinical and …
[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …
pathological conditions, four-chamber heart models have only been addressed recently; …
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …
accurately modeling their arrangement is essential for simulating heart electrophysiology …
Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function
M Fedele, A Quarteroni - International Journal for Numerical …, 2021 - Wiley Online Library
In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …
computational mesh is crucially important. In practice, the input is typically a set of …
Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems
Abstract Development of cardiac fibrosis and arrhythmias is controlled by the activity of and
communication between cardiomyocytes and fibroblasts in the heart. Myocyte-fibroblast …
communication between cardiomyocytes and fibroblasts in the heart. Myocyte-fibroblast …
[HTML][HTML] Fibroblast–myocyte electrotonic coupling: does it occur in native cardiac tissue?
P Kohl, RG Gourdie - Journal of molecular and cellular cardiology, 2014 - Elsevier
Heterocellular electrotonic coupling between cardiac myocytes and non-excitable
connective tissue cells has been a long-established and well-researched fact in vitro …
connective tissue cells has been a long-established and well-researched fact in vitro …
Three‐dimensional integrated functional, structural, and computational mapping to define the structural “fingerprints” of heart‐specific atrial fibrillation drivers in human …
Background Structural remodeling of human atria plays a key role in sustaining atrial
fibrillation (AF), but insufficient quantitative analysis of human atrial structure impedes the …
fibrillation (AF), but insufficient quantitative analysis of human atrial structure impedes the …
Pro‐arrhythmogenic effects of atrial fibrillation‐induced electrical remodelling: insights from the three‐dimensional virtual human atria
Key points• Previous studies have shown that atrial electrical properties are altered
(remodelled) by atrial fibrillation (AF) and that the recurrence of AF is high following …
(remodelled) by atrial fibrillation (AF) and that the recurrence of AF is high following …
[HTML][HTML] Benchmarking electrophysiological models of human atrial myocytes
M Wilhelms, H Hettmann, MM Maleckar… - Frontiers in …, 2013 - frontiersin.org
Mathematical modeling of cardiac electrophysiology is an insightful method to investigate
the underlying mechanisms responsible for arrhythmias such as atrial fibrillation (AF). In past …
the underlying mechanisms responsible for arrhythmias such as atrial fibrillation (AF). In past …