Astrocyte-immune cell interactions in physiology and pathology

RT Han, RD Kim, AV Molofsky, SA Liddelow - Immunity, 2021 - cell.com
Astrocytes play both physiological and pathological roles in maintaining central nervous
system (CNS) function. Here, we review the varied functions of astrocytes and how these …

Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker

Z Yang, KKW Wang - Trends in neurosciences, 2015 - cell.com
Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) III protein uniquely found
in astrocytes in the central nervous system (CNS), non-myelinating Schwann cells in the …

Astrocytes in neurodegenerative disease

H Phatnani, T Maniatis - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Astrocytes contribute to the maintenance of the health and function of the central nervous
system (CNS). Thus, it is not surprising that these multifunctional cells have been implicated …

GFAP in health and disease

J Middeldorp, EM Hol - Progress in neurobiology, 2011 - Elsevier
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …

Astrocytes and disease: a neurodevelopmental perspective

AV Molofsky, R Krenick, E Ullian, H Tsai… - Genes & …, 2012 - genesdev.cshlp.org
Astrocytes are no longer seen as a homogenous population of cells. In fact, recent studies
indicate that astrocytes are morphologically and functionally diverse and play critical roles in …

[HTML][HTML] Isolation and culture of mouse cortical astrocytes

S Schildge, C Bohrer, K Beck… - Journal of visualized …, 2013 - ncbi.nlm.nih.gov
Astrocytes are an abundant cell type in the mammalian brain, yet much remains to be
learned about their molecular and functional characteristics. In vitro astrocyte cell culture …

Astrocyte–neuron metabolic relationships: for better and for worse

I Allaman, M Bélanger, PJ Magistretti - Trends in neurosciences, 2011 - cell.com
In recent years, previously unsuspected roles of astrocytes have been revealed, largely
owing to the development of new tools enabling their selective study in situ. These exciting …

Intermediate filaments play a pivotal role in regulating cell architecture and function

J Lowery, ER Kuczmarski, H Herrmann… - Journal of Biological …, 2015 - ASBMB
Intermediate filaments (IFs) are composed of one or more members of a large family of
cytoskeletal proteins, whose expression is cell-and tissue type-specific. Their importance in …

Large potentials of small heat shock proteins

EV Mymrikov, AS Seit-Nebi… - Physiological …, 2011 - journals.physiology.org
Modern classification of the family of human small heat shock proteins (the so-called HSPB)
is presented, and the structure and properties of three members of this family are analyzed …

Introducing intermediate filaments: from discovery to disease

JE Eriksson, T Dechat, B Grin… - The Journal of …, 2009 - Am Soc Clin Investig
It took more than 100 years before it was established that the proteins that form intermediate
filaments (IFs) comprise a unified protein family, the members of which are ubiquitous in …