Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
Obstructive sleep apnea: current perspectives
AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …
safety, and economic consequences. On an individual level, the causes and consequences …
International consensus statement on obstructive sleep apnea
JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …
allows for consolidation and determination of the key factors important for clinical …
Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches
AV Zinchuk, MJ Gentry, J Concato, HK Yaggi - Sleep medicine reviews, 2017 - Elsevier
Obstructive sleep apnea (OSA) is a complex and heterogeneous disorder and the apnea
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …
Personalized management approach for OSA
JC Carberry, J Amatoury, DJ Eckert - Chest, 2018 - Elsevier
OSA is a heterogeneous disorder. If left untreated, it has major health, safety, and economic
consequences. In addition to varying levels of impairment in pharyngeal anatomy …
consequences. In addition to varying levels of impairment in pharyngeal anatomy …
Apnea–hypopnea event duration predicts mortality in men and women in the sleep heart health study
MP Butler, JT Emch, M Rueschman… - American journal of …, 2019 - atsjournals.org
Rationale: Obstructive sleep apnea is a risk factor for mortality, but its diagnostic metric—the
apnea–hypopnea index—is a poor risk predictor. The apnea–hypopnea index does not …
apnea–hypopnea index—is a poor risk predictor. The apnea–hypopnea index does not …
Endotypes and phenotypes in obstructive sleep apnea
A Malhotra, O Mesarwi, JL Pepin… - Current opinion in …, 2020 - journals.lww.com
OSA is a heterogeneous disease with highly varying underlying mechanisms. OSA has
variable clinical manifestations with definable subsets having risk of particular …
variable clinical manifestations with definable subsets having risk of particular …
More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea
Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
Recent advancements in treating sleep disorders in co-occurring PTSD
PJ Colvonen, LD Straus, C Stepnowsky… - Current psychiatry …, 2018 - Springer
Abstract Purpose of Review Comorbidity of posttraumatic stress disorder (PTSD) and
insomnia, nightmares, and obstructive sleep apnea (OSA) is high. We review recent …
insomnia, nightmares, and obstructive sleep apnea (OSA) is high. We review recent …
Targeting endotypic traits with medications for the pharmacological treatment of obstructive sleep apnea. A review of the current literature
L Taranto-Montemurro, L Messineo… - Journal of clinical …, 2019 - mdpi.com
Obstructive sleep apnea (OSA) is a highly prevalent condition with few therapeutic options.
To date there is no approved pharmacotherapy for this disorder, but several attempts have …
To date there is no approved pharmacotherapy for this disorder, but several attempts have …