Paraventricular hypothalamic mechanisms of chronic stress adaptation

JP Herman, JG Tasker - Frontiers in endocrinology, 2016 - frontiersin.org
The hypothalamic paraventricular nucleus (PVN) is the primary driver of hypothalamo–
pituitary–adrenocortical (HPA) responses. At least part of the role of the PVN is managing …

Effects of stress on alcohol drinking: a review of animal studies

HC Becker, MF Lopez, TL Doremus-Fitzwater - Psychopharmacology, 2011 - Springer
Rationale While stress is often proposed to play a significant role in influencing alcohol
consumption, the relationship between stress and alcohol is complex and poorly …

Chronic stress and hippocampal dendritic complexity: Methodological and functional considerations

CD Conrad, JB Ortiz, JM Judd - Physiology & behavior, 2017 - Elsevier
The current understanding of how chronic stress impacts hippocampal dendritic arbor
complexity and the subsequent relationship to hippocampal-dependent spatial memory is …

Sex differences in risk and resilience: stress effects on the neural substrates of emotion and motivation

CL Wellman, DA Bangasser, JL Bollinger… - Journal of …, 2018 - Soc Neuroscience
Risk for stress-sensitive psychopathologies differs in men and women, yet little is known
about sex-dependent effects of stress on cellular structure and function in corticolimbic …

Chronic social isolation and chronic variable stress during early development induce later elevated ethanol intake in adult C57BL/6J mice

MF Lopez, TL Doremus-Fitzwater, HC Becker - Alcohol, 2011 - Elsevier
Experience with stress situations during early development can have long-lasting effects on
stress-and anxiety-related behaviors. Importantly, this can also favor drug self …

Real-time in vivo two-photon imaging study reveals decreased cerebro-vascular volume and increased blood-brain barrier permeability in chronically stressed mice

S Lee, BM Kang, JH Kim, J Min, HS Kim, H Ryu… - Scientific reports, 2018 - nature.com
Chronic stress disrupts brain homeostasis and adversely affects the cerebro-vascular
system. Even though the effects of chronic stress on brain system have been extensively …

Chronic variable stress alters hypothalamic-pituitary-adrenal axis function in the female mouse

AP Borrow, AL Heck, AM Miller, JA Sheng… - Physiology & …, 2019 - Elsevier
Chronic stress is often associated with a dysregulation of the hypothalamic-pituitary-adrenal
(HPA) axis, which can greatly increase risk for a number of stress-related diseases …

The development of compulsive coping behaviour is associated with a downregulation of Arc in a Locus Coeruleus neuronal ensemble

C Velazquez-Sanchez, L Muresan… - …, 2023 - nature.com
Some compulsive disorders have been considered to stem from the loss of control over
coping strategies, such as displacement. However, the cellular mechanisms involved in the …

Effects of stress on the structure and function of the medial prefrontal cortex: Insights from animal models

CL Wellman, JL Bollinger, KM Moench - International review of …, 2020 - Elsevier
Stress alters both cognitive and emotional function, and increases risk for a variety of
psychological disorders, such as depression and posttraumatic stress disorder. The …

[HTML][HTML] Chronic stress produces enduring sex-and region-specific alterations in novel stress-induced c-Fos expression

KM Moench, MR Breach, CL Wellman - Neurobiology of stress, 2019 - Elsevier
Prolonged or repeated exposure to stress increases risk for a variety of psychological
disorders, many of which are marked by dysfunction of corticolimbic brain regions. Notably …