Genetics in conservation management: revised recommendations for the 50/500 rules, Red List criteria and population viability analyses

R Frankham, CJA Bradshaw, BW Brook - Biological Conservation, 2014 - Elsevier
Conservation managers typically need to make prompt decisions based on limited
information and resources. Consequently, generalisations have essential roles in guiding …

Genetic adaptation to captivity in species conservation programs

R Frankham - Molecular ecology, 2008 - Wiley Online Library
As wild environments are often inhospitable, many species have to be captive‐bred to save
them from extinction. In captivity, species adapt genetically to the captive environment and …

Quantitative genetic analyses of complex behaviours in Drosophila

RRH Anholt, TFC Mackay - Nature Reviews Genetics, 2004 - nature.com
Behaviours are exceptionally complex quantitative traits. Sensitivity to environmental
variation and genetic background, the presence of sexual dimorphism, and the widespread …

Effects of genetic drift and gene flow on the selective maintenance of genetic variation

B Star, HG Spencer - Genetics, 2013 - academic.oup.com
Explanations for the genetic variation ubiquitous in natural populations are often classified
by the population–genetic processes they emphasize: natural selection or mutation and …

Widespread selective sweeps affecting microsatellites in Drosophila populations adapting to captivity: implications for captive breeding programs

ME Montgomery, LM Woodworth, PR England… - Biological …, 2010 - Elsevier
Many threatened species are being maintained in captivity to save them from extinction,
often with the eventual aim of reintroduction. The objective of genetic management in …

Relaxation of Selection With Equalization of Parental Contributions in Conservation Programs: An Experimental Test With Drosophila melanogaster

ST Rodríguez-Ramilo, P Moran, A Caballero - Genetics, 2006 - academic.oup.com
Equalization of parental contributions is one of the most simple and widely recognized
methods to maintain genetic diversity in conservation programs, as it halves the rate of …

Genetic load in subdivided populations: interactions between the migration rate, the size and the number of subpopulations

K Theodorou, D Couvet - Heredity, 2006 - nature.com
We assess the relative importance of migration rate, size and number of subpopulations on
the genetic load of subdivided populations. Using diffusion approximations, we show that in …

No evidence for optimal fitness at intermediate levels of inbreeding in Drosophila melanogaster

SP Robinson, WJ Kennington… - Biological Journal of …, 2009 - academic.oup.com
Optimal outbreeding theory predicts fitness benefits to intermediate levels of inbreeding. In
the present study, we test for linear (consistent with inbreeding depression) and nonlinear …

Genetic architecture of reproductive fitness and its consequences

R Frankham - Adaptation and fitness in animal populations …, 2009 - Springer
Reproductive fitness characters are crucial in animal and plant breeding, evolutionary
genetics and conservation biology. However, the nature of their variation is not well …

EVIDENCE OF SUSCEPTIBILITY AND RESISTANCE TO CRYPTIC X‐LINKED MEIOTIC DRIVE IN NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER

FA Reed, RG Reeves, CF Aquadro - Evolution, 2005 - academic.oup.com
There is mounting evidence consistent with a general role of positive selection acting on the
Drosophila melanogaster X‐chromosome. However, this positive selection need not …