There is much promise in the use of immunotherapy for the treatment of cancer. Approaches
such as those using antibodies or adoptive cell transfer can mediate complete tumor …

Innate immune sensors that detect nucleic acids are attractive targets for therapeutic
intervention because of their diverse roles in many disease processes. In detecting RNA and …

Immunomodulatory therapies are becoming a paradigm-shifting treatment modality for
cancer. Despite promising clinical results, cancer immunotherapy is accompanied with off …

Triple-negative breast cancer (TNBC) due to lack of clear target and notorious “cold” tumor
microenvironment (TME) is one of the most intractable and lethal malignancies. Tuning …

Smart nanorobots have emerged as novel drug delivery platforms in nanomedicine,
potentially improving anti‐cancer efficacy and reducing side effects. In this study, an …

In clinical settings, cancer vaccines as monotherapies have displayed limited success
compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the …

Immunostimulatory CpG oligonucleotides (ODN) activate cells that express TLR9 and have
been shown to improve the host's response to tumor Ags. Unfortunately, the …

Photothermal therapy (PTT) can be an effective antitumor therapy, but it may not completely
eliminate tumor cells, leading to the risk of recurrence or metastasis. Here we describe …

Intratumoral immune activation can induce local and systemic antitumor immunity.
Imiquimod is a cream-formulated, TLR7 agonist that is Food and Drug Administration …

Immunotherapy is a rapidly developing area of cancer treatment due to its higher specificity
and potential for greater efficacy than traditional therapies. Immune cell modulation through …