Endothelium structure and function in kidney health and disease

N Jourde-Chiche, F Fakhouri, L Dou, J Bellien… - Nature Reviews …, 2019 - nature.com
The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

[HTML][HTML] The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on …

C Vlachopoulos, P Xaplanteris, V Aboyans… - Atherosclerosis, 2015 - Elsevier
While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Association of COVID‐19 with impaired endothelial glycocalyx, vascular function and myocardial deformation 4 months after infection

V Lambadiari, A Mitrakou, A Kountouri… - European journal of …, 2021 - Wiley Online Library
Aims SARS‐CoV‐2 infection may lead to endothelial and vascular dysfunction. We
investigated alterations of arterial stiffness, endothelial coronary and myocardial function …

The role of ventricular–arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of …

I Ikonomidis, V Aboyans, J Blacher… - European journal of …, 2019 - Wiley Online Library
Ventricular–arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic
mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment …

Targeting vascular (endothelial) dysfunction

A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …

[HTML][HTML] Endothelial glycocalyx

CA Foote, RN Soares, FI Ramirez-Perez… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …

Endothelial dysfunction: clinical implications in cardiovascular disease and therapeutic approaches

KH Park, WJ Park - Journal of Korean medical science, 2015 - synapse.koreamed.org
Atherosclerosis is a chronic progressive vascular disease. It starts early in life, has a long
asymptomatic phase, and a progression accelerated by various cardiovascular risk factors …

Glycocalyx and sepsis-induced alterations in vascular permeability

C Chelazzi, G Villa, P Mancinelli, AR De Gaudio… - Critical care, 2015 - Springer
Endothelial cells line the inner portion of the heart, blood vessels, and lymphatic vessels; a
basal membrane of extracellular matrix lines the extraluminal side of endothelial cells. The …

Endothelial dysfunction and cardiovascular disease

R Jay Widmer, A Lerman - Global Cardiology Science and Practice, 2014 - qscience.com
The endothelium, by area alone, is one of the largest organs in the body comprised of up to
trillion cells, weighing over 1 kg, and covering nearly 3 m2 in a 70 kg male. 1, 2 Moreover, it …

Endothelial dysfunction: the early predictor of atherosclerosis

M Mudau, A Genis, A Lochner… - Cardiovascular journal of …, 2012 - journals.co.za
Since the discovery in the 1980s that nitric oxide (NO) is in fact the elusive endothelium-
derived relaxing factor, it has become evident that NO is not only a major cardiovascular …