In light of pioneering findings in the 1980s and an estimation of more than 130 million global
annual births, umbilical cord blood (UCB) is considered to be the most plentiful reservoir of …

Perinatal brain injury is a leading cause of death and disability in children. Hypoxic-ischemic
encephalopathy in full term infants, and white matter injury in premature infants are most …

Mesenchymal stem cells (MSCs) are known to support the characteristic properties of
hematopoietic stem and progenitor cells (HSPCs) in the bone marrow hematopoietic …

The application of umbilical cord blood (UCB) as an important source of hematopoietic stem
and progenitor cells (HSPCs) for hematopoietic reconstitution in the clinical context has …

Cell based therapies are being assessed for their therapeutic potential across a variety of
diseases. Gestational tissues are attractive sources for cell therapy. The large number of …

Mesenchymal stem cells (MSCs) are a heterogeneous cellular population containing
different progenitors able to repair tissues, support hematopoiesis, and modulate immune …

Umbilical cord blood (UCB) is now widely used as an alternative hematopoietic stem cell
source for patients lacking closely matched related or unrelated adult donors. UCB …

Umbilical cord blood (UCB) engraftment is in part limited by graft cell dose, generally one
log less than that of bone marrow (BM)/peripheral blood (PB) cell grafts. Strategies toward …

Clinical cord blood (CB) hematopoietic cell transplantation (HCT) has progressed well since
the initial successful CB HCT that saved the life of a young boy with Fanconi anemia. The …

FOXP3 is the transcription factor ruling regulatory T cell function and maintenance of
peripheral immune tolerance, and mutations in its coding gene causes IPEX autoimmune …