Unprecedented advances in secondary prevention have greatly improved the prognosis of
cardiovascular diseases (CVDs); however, CVDs remain a leading cause of death globally …

Carotid artery stenosis (CAS), an atherosclerotic disease of the carotid artery, is one of the
leading causes of transient ischemic attacks (TIA) and cerebrovascular attacks (CVA). The …

Indications for intervention in hemodynamically relevant carotid artery stenosis (carotid
endarterectomy or stenting) are primarily based on a degree of stenosis and …

The inflammatory response associated with myocardial and brain ischemia/reperfusion
injury (IRI) is a critical determinant of tissue necrosis, functional organ recovery, and long …

Cancer cells evade the immune system through a variety of different mechanisms, including
the inhibition of antitumor effector T cells via checkpoint ligand–receptor interaction …

Atherosclerotic cardiovascular diseases (ASCVDs) are the most common and severe public
health problem nowadays. Osteopontin (OPN) is a multifunctional glycoprotein highly …

The death, disability and economic cost of stroke are enormous. Indeed, among the 16
million people worldwide who suffer a stroke'annually, nearly six million die, and another …

Atherosclerosis is a chronic long-lasting vascular disease leading to myocardial infarction
and stroke. Vulnerable atherosclerotic (AS) plaques are responsible for these life …

Statins are effective lipid-lowering drugs with a good safety profile that have become, over
the years, the first-line therapy for patients with dyslipidemia and a real cornerstone of …

Background Inflammation is central to the pathogenesis of many diseases. Supplementation
with selenium and coenzyme Q10 has been shown to reduce cardiovascular mortality, and …