Immune system modulation and viral persistence in bats: understanding viral spillover

S Subudhi, N Rapin, V Misra - Viruses, 2019 - mdpi.com
Bats harbor a myriad of viruses and some of these viruses may have spilled over to other
species including humans. Spillover events are rare and several factors must align to create …

Evolution of pathogen tolerance and emerging infections: A missing experimental paradigm

S Seal, G Dharmarajan, I Khan - Elife, 2021 - elifesciences.org
Researchers worldwide are repeatedly warning us against future zoonotic diseases
resulting from humankind's insurgence into natural ecosystems. The same zoonotic …

Nipah virus dynamics in bats and implications for spillover to humans

JH Epstein, SJ Anthony, A Islam… - Proceedings of the …, 2020 - National Acad Sciences
Nipah virus (NiV) is an emerging bat-borne zoonotic virus that causes near-annual
outbreaks of fatal encephalitis in South Asia—one of the most populous regions on Earth. In …

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

CE Brook, M Boots, K Chandran, AP Dobson… - Elife, 2020 - elifesciences.org
Bats host virulent zoonotic viruses without experiencing disease. A mechanistic
understanding of the impact of bats' virus hosting capacities, including uniquely constitutive …

Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats

SA Riesle-Sbarbaro, G Wibbelt, A Düx… - Nature …, 2024 - nature.com
The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African
countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology …

Sampling to elucidate the dynamics of infections in reservoir hosts

RK Plowright, DJ Becker… - … Transactions of the …, 2019 - royalsocietypublishing.org
The risk of zoonotic spillover from reservoir hosts, such as wildlife or domestic livestock, to
people is shaped by the spatial and temporal distribution of infection in reservoir …

Setting the terms for zoonotic diseases: effective communication for research, conservation, and public policy

JT Shapiro, L Víquez-R, S Leopardi, A Vicente-Santos… - Viruses, 2021 - mdpi.com
Many of the world's most pressing issues, such as the emergence of zoonotic diseases, can
only be addressed through interdisciplinary research. However, the findings of …

Longitudinal monitoring in Cambodia suggests higher circulation of alpha and betacoronaviruses in juvenile and immature bats of three species

J Cappelle, N Furey, T Hoem, TP Ou, T Lim, V Hul… - Scientific Reports, 2021 - nature.com
Recent studies suggest that coronaviruses circulate widely in Southeast Asian bat species
and that the progenitors of the SARS-Cov-2 virus could have originated in rhinolophid bats …

Seasonality of coronavirus shedding in tropical bats

L Joffrin, AOG Hoarau, E Lagadec… - Royal Society …, 2022 - royalsocietypublishing.org
Anticipating cross-species transmission of zoonotic diseases requires an understanding of
pathogen infection dynamics within natural reservoir hosts. Although bats might be a source …

Henipavirus immune evasion and pathogenesis mechanisms: lessons learnt from natural infection and animal models

P Lawrence, B Escudero-Pérez - Viruses, 2022 - mdpi.com
Nipah henipavirus (NiV) and Hendra henipavirus (HeV) are zoonotic emerging
paramyxoviruses causing severe disease outbreaks in humans and livestock, mostly in …