Giardia duodenalis: biology and pathogenesis

RD Adam - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Giardia duodenalis captured the attention of Leeuwenhoek in 1681 while he was examining
his own diarrheal stool, but, ironically, it did not really gain attention as a human pathogen …

The costs and benefits of sex: new insights from old asexual lineages

R Butlin - Nature Reviews Genetics, 2002 - nature.com
Discussions that are aimed at understanding the maintenance of sexual reproduction are in
a bit of a quagmire owing to the many competing theories that have been proposed. Also …

Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga

JF Flot, B Hespeels, X Li, B Noel, I Arkhipova… - Nature, 2013 - nature.com
Loss of sexual reproduction is considered an evolutionary dead end for metazoans, but
bdelloid rotifers challenge this view as they appear to have persisted asexually for millions …

Identification of Zoonotic Genotypes of Giardia duodenalis

H Sprong, SM Cacciò… - PLoS neglected …, 2009 - journals.plos.org
Giardia duodenalis, originally regarded as a commensal organism, is the etiologic agent of
giardiasis, a gastrointestinal disease of humans and animals. Giardiasis causes major …

The population genetics of clonal and partially clonal diploids

F Balloux, L Lehmann, T de Meeûs - Genetics, 2003 - academic.oup.com
The consequences of variable rates of clonal reproduction on the population genetics of
neutral markers are explored in diploid organisms within a subdivided population (island …

Phylogenetic relationships between parthenogens and their sexual relatives: the possible routes to parthenogenesis in animals

JC Simon, F Delmotte, C Rispe… - Biological Journal of the …, 2003 - academic.oup.com
In theory, parthenogenetic lineages have low evolutionary potential because they inexorably
accumulate deleterious mutations and do not generate much genotypic diversity. As a result …

Sexual Cycle of Cryptococcus neoformans var. grubii and Virulence of Congenic a and α Isolates

K Nielsen, GM Cox, P Wang, DL Toffaletti… - Infection and …, 2003 - Am Soc Microbiol
Cryptococcus neoformans is a human-pathogenic fungus that has evolved into three distinct
varieties that infect most prominently the central nervous system. A sexual cycle involving …

Genomic signatures of ancient asexual lineages

BB Normark, OP Judson… - Biological Journal of the …, 2003 - academic.oup.com
Ancient asexuals–organisms that have lived without sex for millions of years–offer unique
opportunities for discriminating among the various theories of the maintenance of sex. The …

Transitions to asexuality result in excess amino acid substitutions

S Paland, M Lynch - Science, 2006 - science.org
Theory predicts that linkage between genetic loci reduces the efficiency of purifying
selection. Because of the permanent linkage of all heritable genetic material, asexual …

Population genetics provides evidence for recombination in Giardia

MA Cooper, RD Adam, M Worobey, CR Sterling - Current Biology, 2007 - cell.com
Giardia lamblia (syn. Giardia intestinalis, Giardia duodenalis) is an enteric protozoan
parasite with two nuclei, and it might be one of the earliest branching eukaryotes [1] …