Cognitively driven pupil modulations reflect certain underlying brain functions. What do
these reflections tell us? Here, we review findings that have identified key roles for three …

The progression of many neurodegenerative diseases is thought to be driven by the
template-directed misfolding, seeded aggregation and cell–cell transmission of …

Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe,
and highly skilled activities, such as a professional playing a tennis match or a violin …

Historically, the locus coeruleus-norepinephrine (LC-NE) system has been implicated in
arousal, but recent findings suggest that this system plays a more complex and specific role …

A major feature of Alzheimer's disease (AD) is the loss of noradrenergic locus coeruleus
(LC) projection neurons that mediate attention, memory, and arousal. However, the extent to …

Psychologists and neuroscientists have had a long-standing interest in the P3, a prominent
component of the event-related brain potential. This review aims to integrate knowledge …

The present edition of The Human Central Nervous System differs considerably from its
predecessors. In previous editions, the text was essentially confined to a section dealing …

Two ideas have dominated neuropsychology concerning the orbitofrontal cortex (OFC). One
holds that OFC regulates emotion and enhances behavioral flexibility through inhibitory …

The locus coeruleus (LC) is the major noradrenergic nucleus of the brain, giving rise to
fibres innervating extensive areas throughout the neuraxis. Recent advances in …

Synapses develop concurrently and at identical rates in different layers of the visual,
somatosensory, motor, and prefrontal areas of the primate cerebral cortex. This isochronic …