Secreted chaperones in neurodegeneration

K Chaplot, TS Jarvela, I Lindberg - Frontiers in aging neuroscience, 2020 - frontiersin.org
Protein homeostasis, or proteostasis, is a combination of cellular processes that govern
protein quality control, namely, protein translation, folding, processing, and degradation …

Equine grass sickness is associated with major abnormalities in the ultrastructure of skeletal neuromuscular junctions

BC McGorum, T Davey, MCM Dosi… - Equine Veterinary …, 2025 - Wiley Online Library
Background Equine grass sickness (EGS) is a frequently fatal multisystem neuropathy of
equids. The aetiology is unknown; proposed causes include toxicoinfection with Clostridium …

[图书][B] Infectious diseases of the horse: diagnosis, pathology, management, and public health

JH van der Kolk, EJBV Kroeze - 2022 - taylorfrancis.com
A clinician and a pathologist collaborate to create a comprehensive yet practical book about
established infectious diseases of horses, categorised according to the different pathogens …

[HTML][HTML] Clinical approach to commonly encountered problems

MT Hines - Equine internal medicine, 2018 - ncbi.nlm.nih.gov
Assessment of body temperature is an essential part of every physical examination. As with
all mammalian species, horses normally maintain their core body temperatures within a …

Exploration of the fecal microbiota and biomarker discovery in equine grass sickness

J Leng, C Proudman, A Darby, F Blow… - Journal of proteome …, 2018 - ACS Publications
Equine grass sickness (EGS) is a frequently fatal disease of horses, responsible for the
death of 1 to 2% of the UK horse population annually. The etiology of this disease is …

Equine dysautonomia

BC McGorum, RS Pirie - Veterinary Clinics: Equine …, 2018 - vetequine.theclinics.com
Equine dysautonomia (ED; also known as equine grass sickness) is a polyneuropathy
affecting both the central and peripheral nervous systems of, almost exclusively, grazing …

Neurotoxic phospholipase A2: A proposed cause of equine grass sickness and other animal dysautonomias (multiple system neuropathies)

B McGorum, RS Pirie, L Bano, T Davey… - Equine Veterinary …, 2024 - research.ed.ac.uk
McGorum, B, Pirie, RS, Bano, L, Davey, T, Harris, J & Montecucco, C 2024,'Neurotoxic
phospholipase A2: A proposed cause of equine grass sickness and other animal …

Standing gustatory papillae biopsy procedure for antemortem diagnosis of equine grass sickness

E Quéré, C Volmer… - Journal of the American …, 2024 - Am Vet Med Assoc
OBJECTIVE Diagnosing equine grass sickness (EGS) requires histopathological evidence
of chromatolysis and/or neuronal loss in peripheral autonomic ganglia. Previous …

Histological assessment of β‐amyloid precursor protein immunolabelled rectal biopsies aids diagnosis of equine grass sickness

RC Jago, S Scholes, TS Mair… - Equine veterinary …, 2018 - Wiley Online Library
Background An accurate, minimally invasive, ante‐mortem diagnostic test for equine grass
sickness (EGS) is currently lacking. Although histological examination of haematoxylin and …

The proSAAS chaperone provides neuroprotection and attenuates transsynaptic α-synuclein spread in rodent models of Parkinson's disease

I Lindberg, Z Shu, H Lam, M Helwig… - Journal of …, 2022 - content.iospress.com
Background: Parkinson's disease involves aberrant aggregation of the synaptic protein
alpha-synuclein (aSyn) in the nigrostriatal tract. We have previously shown that proSAAS, a …