Chiral separation has already become a crucial topic for effectively utilizing superfluous
racemates synthesized by chemical means and satisfying the growing requirements for …

Continuous crystallization has always been a hot topic in industrial crystallization. Many
efforts have been made to improve the continuous crystallization, either by designing novel …

Crystallization is an important unit operation in the pharmaceutical industry. At present, most
pharmaceutical crystallization processes are performed in batches. However, due to product …

Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …

Conglomerate crystallization is the spontaneous generation of individually enantioenriched
crystals from a nonenantioenriched material. This behavior is responsible for spontaneous …

The human body is amazingly chirally selective, and consequently enantiopure drugs are
essential for treating disease. Nearly 50% of drugs are chiral wherein pharmacological …

Continuous crystallization process has potential advantages such as lower cost and
improved flexibility in pharmaceutical production when compared to batch crystallization. A …

Preferential crystallization can be a highly efficient method of producing enantiopure
chemicals at large scale. While most preferential crystallization processes have been …

The first continuous crystallization of a metastable polymorphic form of an active
pharmaceutical ingredient is reported. Paracetamol form II, which displays enhanced …

Obtaining pure enantiomers is crucial since the two enantiomers of chiral compounds can
exhibit vastly different optical, biological, and pharmacological properties. Two mixed …