Updating the clinical application of blood biomarkers and their algorithms in the diagnosis and surveillance of hepatocellular carcinoma: a critical review

E Shahini, G Pasculli, AG Solimando, C Tiribelli… - International Journal of …, 2023 - mdpi.com
The most common primary liver cancer is hepatocellular carcinoma (HCC), and its mortality
rate is increasing globally. The overall 5-year survival of patients with liver cancer is …

[HTML][HTML] Hepatitis C Virus: Insights Into Its History, Treatment, Challenges, and Future Directions

LA Bernal, V Soti - Cureus, 2023 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a global public health concern with significant impacts. It primarily
spreads through blood-to-blood contact, such as sharing needles among drug users. Given …

Raman scattering-based optical sensing of chronic liver diseases

K Alkhuder - Photodiagnosis and Photodynamic Therapy, 2023 - Elsevier
Chronic liver diseases (CLDs) are a major public health problem. Despite the progress
achieved in fighting against viral hepatitis, the emergence of non-alcoholic fatty liver disease …

Epidemiology of Hepatitis C over 28 years of monitoring Canadian blood donors: Insight into a low-risk undiagnosed population

SF O'Brien, B Ehsani-Moghaddam, L Osmond, W Fan… - BMC Public Health, 2024 - Springer
Background Hepatitis C is a blood-borne infection with the hepatitis C virus (HCV) that can
progress to cirrhosis and liver cancer. About 70%(50–80%) of infections become chronic …

The COVID-19 Pandemic Affected Hepatitis C Virus Circulation and Genotypic Frequencies—Implications for Hepatitis C Prevention, Treatment and Research

JD Oliveira Correa, JAB Chies - Epidemiologia, 2024 - mdpi.com
Hepatitis C is regarded as a global health issue caused by hepatitis C virus (HCV) infection.
HCV is targeted for elimination by 2030 as a global public health goal. However, the COVID …

The role of microRNAs in hepatocellular cancer: a narrative review focused on tumor microenvironment and drug resistance

A Tavakoli Pirzaman, A Alishah… - … in Cancer Research …, 2024 - journals.sagepub.com
Globally, hepatic cancer ranks fourth in terms of cancer-related mortality and is the sixth
most frequent kind of cancer. Around 80% of liver cancers are hepatocellular carcinomas …

Antiviral treatment significantly reduces the levels of CXCL9, CXCL10 and CXCL11 in chronic hepatitis C

L Radmanić, P Šimičić, K Bodulić, A Vince… - Cytokine, 2024 - Elsevier
In this study, we aimed to elucidate the changes in the immune response during antiviral
treatment of patients with chronic hepatitis C, with an emphasis on the chemokine dynamics …

Efficacy and safety of first-line treatments for advanced hepatocellular carcinoma patients: a systematic review and network meta-analysis

J Li, B Yang, Z Teng, Y Liu, D Li, X Qu - Frontiers in Immunology, 2024 - frontiersin.org
Background The first-line treatment for advanced hepatocellular carcinoma has evolved
significantly. This study aimed to identify the most beneficial regimen. Methods A systematic …

Diversified applications of hepatocellular carcinoma medications: molecular-targeted, immunotherapeutic, and combined approaches

H Chen, H Liu, X Zhang, S Wang, C Liu, K An… - Frontiers in …, 2024 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the primary forms of liver cancer and is currently
the sixth most prevalent malignancy worldwide. In addition to surgical interventions, effective …

Update on Hepatitis C Vaccine: Results and Challenges

AR Garbuglia, S Pauciullo, V Zulian, P Del Porto - Viruses, 2024 - pmc.ncbi.nlm.nih.gov
Therapy against the Hepatitis C virus (HCV) has significantly improved with the introduction
of direct-acting antiviral drugs (DAAs), achieving over 95% sustained virological response …