Posttranslational modifications (PTMs) modulate protein function in most eukaryotes and
have a ubiquitous role in diverse range of cellular functions. Identification, characterization …

Thyroid autoimmunity involves loss of tolerance to thyroid proteins in genetically susceptible
individuals in association with environmental factors. In central tolerance, intrathymic …

The immune system is highly controlled and fine-tuned by glycosylation, through the
addition of a diversity of carbohydrates structures (glycans) to virtually all immune cell …

Glycosylation of eukaryotic virus particles is common and influences their uptake, trafficking,
and immune recognition. In contrast, glycosylation of bacteriophage particles has not been …

Chikungunya virus (CHIKV) is a mosquito‐borne pathogen that has a major health impact in
humans and causes acute febrile illness in humans accompanied by joint pains and, in …

Chikungunya virus (CHIKV), a member of Alphavirus genus, is responsible for chikungunya
fever (CHIKF), which is characterized by the presence of fever, rash, myalgia, and arthralgia …

The majority of the patients affected by acquired thrombotic thrombocytopenic purpura (TTP)
develop autoantibodies directed towards ADAMTS13 that interfere with its von Willebrand …

Changes in cell surface glycosylation are a hallmark of the transition from normal to inflamed
and neoplastic tissue. Tumor-associated carbohydrate antigens (TACAs) challenge our …

All biotherapeutics have the potential to induce an immune response. This immunological
response is complex and, in addition to antibody formation, involves T cell activation and …

Reactivation of latent herpes simplex virus 2 (HSV-2) infections can be characterized by
episodic recurrent genital lesions and/or viral shedding. We hypothesize that infected (HSV …