Astrocytic K+ clearance during disease progression in amyotrophic lateral sclerosis
R Stevenson, E Samokhina, A Mangat, I Rossetti… - Glia, 2023 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which patients lose
motor functions due to progressive loss of motor neurons in the cortex, brainstem, and spinal …
motor functions due to progressive loss of motor neurons in the cortex, brainstem, and spinal …
A method for assessing tissue respiration in anatomically defined brain regions
E Underwood, JB Redell, J Zhao, AN Moore… - Scientific reports, 2020 - nature.com
The survival and function of brain cells requires uninterrupted ATP synthesis. Different brain
structures subserve distinct neurological functions, and therefore have different energy …
structures subserve distinct neurological functions, and therefore have different energy …
Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum
R Gamage, I Rossetti, G Niedermayer, G Münch… - Journal of …, 2023 - Springer
Background Low-grade, chronic inflammation in the central nervous system characterized
by glial reactivity is one of the major hallmarks for aging-related neurodegenerative …
by glial reactivity is one of the major hallmarks for aging-related neurodegenerative …
Astrocytic modulation of cortical oscillations
Brain waves are rhythmic voltage oscillations emerging from the synchronization of
individual neurons into a neuronal network. These oscillations range from slow to fast …
individual neurons into a neuronal network. These oscillations range from slow to fast …
Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a type of motor neuron disease (MND) in which
humans lose motor functions due to progressive loss of motoneurons in the cortex …
humans lose motor functions due to progressive loss of motoneurons in the cortex …
The differential impact of acute microglia activation on the excitability of cholinergic neurons in the mouse medial septum
The medial septal nucleus is one of the basal forebrain nuclei that projects cholinergic input
to the hippocampus and cortex. Two of the hallmarks of Alzheimer's disease (AD) are a …
to the hippocampus and cortex. Two of the hallmarks of Alzheimer's disease (AD) are a …
Starting a Synthetic Biological Intelligence Lab from Scratch
MS Tanveer, D Patel, HE Schweiger… - arXiv preprint arXiv …, 2024 - arxiv.org
With the recent advancements in artificial intelligence, researchers and industries are
deploying gigantic models trained on billions of samples. While training these models …
deploying gigantic models trained on billions of samples. While training these models …
Extending the life span of acute neuronal tissue for imaging and electrophysiological studies
Slice preparations of neuronal tissue are among the most commonly used experimental
approaches in the field of neuroscience. They are employed for a variety of techniques …
approaches in the field of neuroscience. They are employed for a variety of techniques …
Analyzing the size, shape, and directionality of networks of coupled astrocytes
S Condamine, D Verdier… - Journal of Visualized …, 2018 - pmc.ncbi.nlm.nih.gov
It has become increasingly clear that astrocytes modulate neuronal function not only at the
synaptic and single-cell levels, but also at the network level. Astrocytes are strongly …
synaptic and single-cell levels, but also at the network level. Astrocytes are strongly …
Potassium homeostasis during disease progression of Alzheimers Disease
Alzheimers disease (AD) is an age-dependent neurodegenerative disorder characterized by
neuronal loss leading to dementia and ultimately death. Whilst the loss of neurons is central …
neuronal loss leading to dementia and ultimately death. Whilst the loss of neurons is central …