The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and
cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the …

Abstract Mammalian SWI/SNF like Brg1/Brm associated factors (BAF) chromatin-remodeling
complexes are able to use energy derived from adenosine triphosphate (ATP) hydrolysis to …

Recent studies suggest that individual subunits of chromatin-remodeling complexes
produce biologically specific meaning in different cell types through combinatorial assembly …

The zebrafish possesses a remarkable capacity of adult heart regeneration, but the
underlying mechanisms are not well understood. Here we report that chromatin remodelling …

Skeletal muscle regeneration is mediated by myoblasts that undergo epigenomic changes
to establish the gene expression program of differentiated myofibers. mSWI/SNF chromatin …

Myogenesis involves the stable commitment of progenitor cells followed by the execution of
myogenic differentiation, processes that are coordinated by myogenic regulatory factors …

Mature vascular smooth muscle cells (VSMC) exhibit a remarkable degree of plasticity, a
characteristic that has intrigued cardiovascular researchers for decades. Recently, it has …

Development of the heart requires recruitment of cardiovascular progenitor cells (CPCs) to
the future heart-forming region. CPCs are the building blocks of the heart, and have the …

Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation.
Fibroblast growth factor (Fgf) signalling cooperates with Tbx transcription factors to promote …

Transcription factors have diverse roles during embryonic development, combinatorially
controlling cellular states in a spatially and temporally defined manner. Resolving the …