Left ventricular non-compaction cardiomyopathy
JA Towbin, A Lorts, JL Jefferies - The Lancet, 2015 - thelancet.com
Left ventricular non-compaction, the most recently classified form of cardiomyopathy, is
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …
Transcription factors of the NFAT family: regulation and function
A Rao, C Luo, PG Hogan - Annual review of immunology, 1997 - annualreviews.org
▪ Abstract As targets for the immunosuppressive drugs cyclosporin A and FK506,
transcription factors of the NFAT (nuclear factor of activated T cells) family have been the …
transcription factors of the NFAT (nuclear factor of activated T cells) family have been the …
Inositol Trisphosphate Receptor Ca2+ Release Channels
The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …
channels localized predominately in the endoplasmic reticulum of all cell types. They …
Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease
MW Berchtold, H Brinkmeier… - Physiological …, 2000 - journals.physiology.org
Mammalian skeletal muscle shows an enormous variability in its functional features such as
rate of force production, resistance to fatigue, and energy metabolism, with a wide spectrum …
rate of force production, resistance to fatigue, and energy metabolism, with a wide spectrum …
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type
Slow-and fast-twitch myofibers of adult skeletal muscles express unique sets of muscle-
specific genes, and these distinctive programs of gene expression are controlled by …
specific genes, and these distinctive programs of gene expression are controlled by …
Regulation of the calmodulin-stimulated protein phosphatase, calcineurin
CB Klee, H Ren, X Wang - Journal of Biological Chemistry, 1998 - ASBMB
The role of protein phosphatases in the regulation of cellular processes is now well
established (1, 2). Calcineurin (also called protein phosphatase 2B), a major calmodulin …
established (1, 2). Calcineurin (also called protein phosphatase 2B), a major calmodulin …
Revisiting the concept of targeting NFAT to control T cell immunity and autoimmune diseases
JU Lee, LK Kim, JM Choi - Frontiers in immunology, 2018 - frontiersin.org
The nuclear factor of activated T cells (NFAT) family of transcription factors, which includes
NFAT1, NFAT2, and NFAT4, are well-known to play important roles in T cell activation. Most …
NFAT1, NFAT2, and NFAT4, are well-known to play important roles in T cell activation. Most …
Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons
A Verkhratsky - Physiological reviews, 2005 - journals.physiology.org
The endoplasmic reticulum (ER) is the largest single intracellular organelle, which is present
in all types of nerve cells. The ER is an interconnected, internally continuous system of …
in all types of nerve cells. The ER is an interconnected, internally continuous system of …
Extensive and divergent effects of sleep and wakefulness on brain gene expression
Sleep is present in all species where it has been studied, but its functions remain unknown.
To investigate what benefits sleep may bring at the cellular level, we profiled gene …
To investigate what benefits sleep may bring at the cellular level, we profiled gene …
Control of aldosterone secretion: a model for convergence in cellular signaling pathways
A Spat, L Hunyady - Physiological reviews, 2004 - journals.physiology.org
Spät, András, and László Hunyady. Control of Aldosterone Secretion: A Model for
Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; …
Convergence in Cellular Signaling Pathways. Physiol Rev 84: 489–539, 2004; …