Sleep viewed as a state of adaptive inactivity
JM Siegel - Nature Reviews Neuroscience, 2009 - nature.com
Sleep is often viewed as a vulnerable state that is incompatible with behaviours that nourish
and propagate species. This has led to the hypothesis that sleep has survived because it …
and propagate species. This has led to the hypothesis that sleep has survived because it …
The mouse thermoregulatory system: Its impact on translating biomedical data to humans
CJ Gordon - Physiology & behavior, 2017 - Elsevier
The laboratory mouse has become the predominant test species in biomedical research.
The number of papers that translate or extrapolate data from mouse to human has grown …
The number of papers that translate or extrapolate data from mouse to human has grown …
Body temperature measurements for metabolic phenotyping in mice
Endothermic organisms rely on tightly balanced energy budgets to maintain a regulated
body temperature and body mass. Metabolic phenotyping of mice, therefore, often includes …
body temperature and body mass. Metabolic phenotyping of mice, therefore, often includes …
Caloric restriction: from soup to nuts
SR Spindler - Ageing research reviews, 2010 - Elsevier
Caloric restriction (CR), reduced protein, methionine, or tryptophan diets; and reduced
insulin and/or IGFI intracellular signaling can extend mean and/or maximum lifespan and …
insulin and/or IGFI intracellular signaling can extend mean and/or maximum lifespan and …
Syndecan-1 is required to maintain intradermal fat and prevent cold stress
Homeostatic temperature regulation is fundamental to mammalian physiology and is
controlled by acute and chronic responses of local, endocrine and nervous regulators. Here …
controlled by acute and chronic responses of local, endocrine and nervous regulators. Here …
Heterothermy in large mammals: inevitable or implemented?
Advances in biologging techniques over the past 20 years have allowed for the remote and
continuous measurement of body temperatures in free‐living mammals. While there is an …
continuous measurement of body temperatures in free‐living mammals. While there is an …
Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertility
Q Wu, BB Whiddon… - Proceedings of the …, 2012 - National Acad Sciences
Leptin-deficient (Lepob/ob) mice are obese, diabetic, and infertile. Ablation of neurons that
make agouti-related protein (AgRP) in moderately obese adult Lepob/ob mice caused …
make agouti-related protein (AgRP) in moderately obese adult Lepob/ob mice caused …
Leptin in teleost fishes: an argument for comparative study
DL Copeland, RJ Duff, Q Liu, J Prokop… - Frontiers in …, 2011 - frontiersin.org
All organisms face tradeoffs with regard to how limited energy resources should be invested.
When is it most favorable to grow, to reproduce, how much lipid should be allocated to …
When is it most favorable to grow, to reproduce, how much lipid should be allocated to …
Epigenetics as a source of variation in comparative animal physiology–or–Lamarck is lookin'pretty good these days
WW Burggren - Journal of Experimental Biology, 2014 - journals.biologists.com
Considerable variation is inherent both within and between comparative physiological data
sets. Known sources for such variation include diet, gender, time of day and season of …
sets. Known sources for such variation include diet, gender, time of day and season of …
[HTML][HTML] Eat, sleep, repeat: the role of the circadian system in balancing sleep–wake control with metabolic need
RC Northeast, VV Vyazovskiy, DA Bechtold - Current Opinion in Physiology, 2020 - Elsevier
Feeding and sleep are behaviours fundamental to survival, and as such are subject to
powerful homeostatic control. Of course, these are mutually exclusive behaviours, and …
powerful homeostatic control. Of course, these are mutually exclusive behaviours, and …