Pathophysiology of RAGE in inflammatory diseases
H Dong, Y Zhang, Y Huang, H Deng - Frontiers in Immunology, 2022 - frontiersin.org
The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
Targeting RAGE signaling in inflammatory disease
BI Hudson, ME Lippman - Annual review of medicine, 2018 - annualreviews.org
The receptor for advanced glycation end-products (RAGE) is a multiligand pattern
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …
recognition receptor implicated in diverse chronic inflammatory states. RAGE binds and …
Apoptosis, autophagy, necroptosis, and cancer metastasis
Z Su, Z Yang, Y Xu, Y Chen, Q Yu - Molecular cancer, 2015 - Springer
Metastasis is a crucial hallmark of cancer progression, which involves numerous factors
including the degradation of the extracellular matrix (ECM), the epithelial-to-mesenchymal …
including the degradation of the extracellular matrix (ECM), the epithelial-to-mesenchymal …
All the “RAGE” in lung disease: The receptor for advanced glycation endproducts (RAGE) is a major mediator of pulmonary inflammatory responses
EA Oczypok, TN Perkins, TD Oury - Paediatric respiratory reviews, 2017 - Elsevier
The receptor for advanced glycation endproducts (RAGE) is a pro-inflammatory pattern
recognition receptor (PRR) that has been implicated in the pathogenesis of numerous …
recognition receptor (PRR) that has been implicated in the pathogenesis of numerous …
S100A8/A9 activate key genes and pathways in colon tumor progression
M Ichikawa, R Williams, L Wang, T Vogl… - Molecular cancer …, 2011 - AACR
The tumor microenvironment plays an important role in modulating tumor progression.
Earlier, we showed that S100A8/A9 proteins secreted by myeloid-derived suppressor cells …
Earlier, we showed that S100A8/A9 proteins secreted by myeloid-derived suppressor cells …
Molecular characteristics of RAGE and advances in small-molecule inhibitors
HJ Kim, MS Jeong, SB Jang - International journal of molecular sciences, 2021 - mdpi.com
Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …
Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis
The receptor for advanced glycation end products (RAGE) is highly expressed in various
cancers and is correlated with poorer outcome in breast and other cancers. Here we tested …
cancers and is correlated with poorer outcome in breast and other cancers. Here we tested …
RAGE inhibitor TTP488 (Azeliragon) suppresses metastasis in triple-negative breast cancer
M Magna, GH Hwang, A McIntosh, K Drews-Elger… - NPJ Breast …, 2023 - nature.com
Triple-negative breast cancer (TNBC) is a highly aggressive and metastatic cancer subtype,
which is generally untreatable once it metastasizes. We hypothesized that interfering with …
which is generally untreatable once it metastasizes. We hypothesized that interfering with …
RAGE expression in human T cells: a link between environmental factors and adaptive immune responses
EM Akirav, P Preston-Hurlburt, J Garyu, O Henegariu… - PloS one, 2012 - journals.plos.org
The Receptor for Advanced Glycation Endproducts (RAGE) is a scavenger ligand that binds
glycated endproducts as well as molecules released during cell death such as S100b and …
glycated endproducts as well as molecules released during cell death such as S100b and …
The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines
RC Chen, PP Yi, RR Zhou, MF Xiao, ZB Huang… - Molecular and cellular …, 2014 - Springer
High mobility group protein box1 (HMGB1) and its receptor—receptor for advanced
glycation end products (RAGE) are pivotal factors in the development and progression of …
glycation end products (RAGE) are pivotal factors in the development and progression of …