Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

Human tissues express cannabinoid CB1 and CB2 receptors that can be activated by
endogenously released 'endocannabinoids' or exogenously administered compounds in a …

The isolation and identification of the discrete plant cannabinoids in marijuana revived
interest in analyzing historical therapeutic claims made for cannabis in clinical case studies …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Background K2 products are synthetic cannabinoid-laced, marijuana-like drugs of abuse,
use of which is often associated with clinical symptoms atypical of marijuana use, including …

Recently, cannabis has been suggested as a potential alternative therapy for refractory
epilepsy, which affects 30% of epilepsy, both adults and children, who do not respond to …

Traditional herbal medicine plays a significant role in the treatment of epilepsy. Though
herbal medicine is widely used in antiepileptic treatment, there is a lack of robust evidence …

Purpose: We assessed the anticonvulsant potential of the phytocannabinoid Δ9‐
tetrahydrocannabivarin (Δ9‐THCV) by investigating its effects in an in vitro piriform cortex …

Cannabis has been used to treat convulsions and other disorders since ancient times. In the
last few decades, preclinical animal studies and clinical investigations have established the …

Cannabinoids and drugs that increase endocannabinoid levels inhibit neuronal excitability
and restrain epileptic seizures through CB1 receptor activation. Nevertheless, the results …