[HTML][HTML] Exosomes and ectosomes in intercellular communication
J Meldolesi - Current Biology, 2018 - cell.com
Exosomes and ectosomes, two distinct types of extracellular vesicles generated by all types
of cell, play key roles in intercellular communication. The formation of these vesicles …
of cell, play key roles in intercellular communication. The formation of these vesicles …
Lymphatic vessels in cancer
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …
nodes that are present in almost every tissue of the human body, acts as an essential …
Exosomes: the next generation of endogenous nanomaterials for advanced drug delivery and therapy
W Liao, Y Du, C Zhang, F Pan, Y Yao, T Zhang, Q Peng - Acta biomaterialia, 2019 - Elsevier
Abstract Development of functional nanomaterials is of great importance and significance for
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
[HTML][HTML] GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain
Extracellular vesicles (EVs) are biological nanoparticles with important roles in intercellular
communication, and potential as drug delivery vehicles. Here we demonstrate a role for the …
communication, and potential as drug delivery vehicles. Here we demonstrate a role for the …
What is the blood concentration of extracellular vesicles? Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer
Circulating biomarkers have a great potential in diagnosing cancer diseases at early stages,
where curative treatment is a realistic possibility. In the recent years, using extracellular …
where curative treatment is a realistic possibility. In the recent years, using extracellular …
[HTML][HTML] Drug delivery systems in regenerative medicine: an updated review
Modern drug discovery methods led to evolving new agents with significant therapeutic
potential. However, their properties, such as solubility and administration-related …
potential. However, their properties, such as solubility and administration-related …
Extracellular vesicle‐mediated delivery of circDYM alleviates CUS‐induced depressive‐like behaviours
X Yu, Y Bai, B Han, M Ju, T Tang… - Journal of …, 2022 - Wiley Online Library
Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and
severely limits psychosocial function and quality of life, but no effective medication is …
severely limits psychosocial function and quality of life, but no effective medication is …
[HTML][HTML] Enhanced loading of functional miRNA cargo via pH gradient modification of extracellular vesicles
Based on their identification as physiological nucleic acid carriers in humans and other
organisms, extracellular vesicles (EVs) have been explored as therapeutic delivery vehicles …
organisms, extracellular vesicles (EVs) have been explored as therapeutic delivery vehicles …
[HTML][HTML] Therapeutic potential of engineered extracellular vesicles
KI Mentkowski, JD Snitzer, S Rusnak, JK Lang - The AAPS journal, 2018 - Springer
Extracellular vesicles (EVs) comprise a heterogeneous group of small membrane vesicles,
including exosomes, which play a critical role in intracellular communication and regulation …
including exosomes, which play a critical role in intracellular communication and regulation …