Malaria during pregnancy

M Fried, PE Duffy - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …

Epidemiology, drug resistance, and pathophysiology of Plasmodium vivax malaria

KK Dayananda, RN Achur… - Journal of vector borne …, 2018 - journals.lww.com
Malaria, caused by the protozoan parasites of the genus Plasmodium, is a major health
problem in many countries of the world. Five parasite species namely, Plasmodium …

[HTML][HTML] Glycosaminoglycans and infection

RS Aquino, PW Park - Frontiers in bioscience (Landmark edition), 2016 - ncbi.nlm.nih.gov
Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular
compartments, at the cell surface, and in the extracellular environment where they interact …

Proteoglycans in host–pathogen interactions: molecular mechanisms and therapeutic implications

AH Bartlett, PW Park - Expert reviews in molecular medicine, 2010 - cambridge.org
Many microbial pathogens subvert proteoglycans for their adhesion to host tissues, invasion
of host cells, infection of neighbouring cells, dissemination into the systemic circulation, and …

Pregnancy Outcome and Placenta Pathology in Plasmodium berghei ANKA Infected Mice Reproduce the Pathogenesis of Severe Malaria in Pregnant Women

R Neres, CRF Marinho, LA Gonçalves, MB Catarino… - PloS one, 2008 - journals.plos.org
Pregnancy-associated malaria (PAM) is expressed in a range of clinical complications that
include increased disease severity in pregnant women, decreased fetal viability, intra …

Antimalarial Activity of Orally Administered Curcumin Incorporated in Eudragit®-Containing Liposomes

E Martí Coma-Cros, A Biosca, E Lantero… - International journal of …, 2018 - mdpi.com
Curcumin is an antimalarial compound easy to obtain and inexpensive, having shown little
toxicity across a diverse population. However, the clinical use of this interesting polyphenol …

Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-α-dependent

YJ Liu, DW Guo, L Tian, DS Shang, WD Zhao, B Li… - Neurobiology of …, 2010 - Elsevier
The mechanism of circulating T cells entry into the brain in Alzheimer's diseases (AD)
remains unclear. Here, we showed that peripheral T cells derived from AD patients …

Plasmodium in the placenta: parasites, parity, protection, prevention and possibly preeclampsia

PE Duffy - Parasitology, 2007 - cambridge.org
The epidemiology of pregnancy malaria infection and disease is complex but reflects
underlying interactions between the Plasmodium falciparum parasite, the mother, and the …

Disruption of Var2csa Gene Impairs Placental Malaria Associated Adhesion Phenotype

NK Viebig, E Levin, S Dechavanne, SJ Rogerson… - PloS one, 2007 - journals.plos.org
Infection with Plasmodium falciparum during pregnancy is one of the major causes of
malaria related morbidity and mortality in newborn and mothers. The complications of …

Microglial TNF-α-dependent elevation of MHC class I expression on brain endothelium induced by amyloid-beta promotes T cell transendothelial migration

YM Yang, DS Shang, WD Zhao, WG Fang… - Neurochemical …, 2013 - Springer
The blood–brain barrier (BBB) normally bars peripheral T lymphocytes from entering the
cerebrum. Interestingly, activated T cells exist as infiltrates in the brains of Alzheimer's …