Regulation of microRNA function in animals

LFR Gebert, IJ MacRae - Nature reviews Molecular cell biology, 2019 - nature.com
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …

[HTML][HTML] Anthropogenic temperature fluctuations and their effect on aquaculture: A comprehensive review

M Mugwanya, MAO Dawood, F Kimera… - Aquaculture and …, 2022 - Elsevier
The reliance of aquaculture production on the ambient environment suggests its
vulnerability to climate change. Global warming has led to the increase in water …

The widespread regulation of microRNA biogenesis, function and decay

J Krol, I Loedige, W Filipowicz - Nature reviews genetics, 2010 - nature.com
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

Long non-coding RNAs and cancer: a new frontier of translational research?

R Spizzo, MI Almeida, A Colombatti, GA Calin - Oncogene, 2012 - nature.com
Tiling array and novel sequencing technologies have made available the transcription
profile of the entire human genome. However, the extent of transcription and the function of …

Viruses, microRNAs, and host interactions

RL Skalsky, BR Cullen - Annual review of microbiology, 2010 - annualreviews.org
One of the most significant recent advances in biomedical research has been the discovery
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …

On the importance of host microRNAs during viral infection

E Girardi, P López, S Pfeffer - Frontiers in genetics, 2018 - frontiersin.org
Every living organism has to constantly face threats from the environment and deal with a
large number of pathogens against which it has to defend itself to survive. Among those …

Emerging roles for natural microRNA sponges

MS Ebert, PA Sharp - Current biology, 2010 - cell.com
Recently, a non-coding RNA expressed from a human pseudogene was reported to regulate
the corresponding protein-coding mRNA by acting as a decoy for microRNAs (miRNAs) that …

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

D Cazalla, T Yario, JA Steitz - Science, 2010 - science.org
T cells transformed by Herpesvirus saimiri express seven viral U-rich noncoding RNAs of
unknown function called HSURs. We noted that conserved sequences in HSURs 1 and 2 …

Structural foundations of RNA silencing by Argonaute

J Sheu-Gruttadauria, IJ MacRae - Journal of molecular biology, 2017 - Elsevier
Nearly every cell in the human body contains a set of programmable gene-silencing proteins
named Argonaute. Argonaute proteins mediate gene regulation by small RNAs and thereby …

Potent degradation of neuronal mi RNA s induced by highly complementary targets

M de la Mata, D Gaidatzis, M Vitanescu, MB Stadler… - EMBO …, 2015 - embopress.org
Micro RNA s (mi RNA s) regulate target mRNA s by silencing them. Reciprocally, however,
target mRNA s can also modulate mi RNA stability. Here, we uncover a remarkable efficacy …