[HTML][HTML] A historical review of brain drug delivery

WM Pardridge - Pharmaceutics, 2022 - mdpi.com
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …

[HTML][HTML] Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles

JT Morton, DM Jin, RH Mills, Y Shao, G Rahman… - Nature …, 2023 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …

[HTML][HTML] Road to the red carpet of edible crickets through integration into the human food chain with biofunctions and sustainability: A review

V Kemsawasd, W Inthachat, U Suttisansanee… - International journal of …, 2022 - mdpi.com
The Food and Agriculture Organization of the United Nations (FAO) estimates that more than
500 million people, especially in Asia and Africa, are suffering from malnutrition. Recently …

[HTML][HTML] Is it time to reconsider the US recommendations for dietary protein and amino acid intake?

M Weiler, SR Hertzler, S Dvoretskiy - Nutrients, 2023 - mdpi.com
Since the US Institute of Medicine's recommendations on protein and amino acid intake in
2005, new information supports the need to re-evaluate these recommendations. New lines …

Advanced theragnostics for the central nervous system (CNS) and neurological disorders using functional inorganic nanomaterials

B Conklin, BM Conley, Y Hou, M Chen… - Advanced Drug Delivery …, 2023 - Elsevier
Various types of inorganic nanomaterials are capable of diagnostic biomarker detection and
the therapeutic delivery of a disease or inflammatory modulating agent. Those multi …

[HTML][HTML] Nutrition, epigenetics, and major depressive disorder: understanding the connection

MA Ortega, Ó Fraile-Martínez, C García-Montero… - Frontiers in …, 2022 - frontiersin.org
Major Depressive Disorder (MDD) entails a multifactorial disorder of rising prevalence.
Nearly 280 million people suffer from this leading cause of disability in the world. Moreover …

Recent advances in colorimetric and fluorometric sensing of neurotransmitters by organic scaffolds

M Chemchem, A Chemchem, B Aydıner… - European Journal of …, 2022 - Elsevier
Neurotransmitters are chemical compounds released by neurons acting as messengers that
transmit signals to other neurons, called postsynaptic neurons, or other types of cells. These …

[HTML][HTML] Synaptic reshaping and neuronal outcomes in the temporal lobe epilepsy

E Ren, G Curia - International Journal of Molecular Sciences, 2021 - mdpi.com
Temporal lobe epilepsy (TLE) is one of the most common types of focal epilepsy,
characterized by recurrent spontaneous seizures originating in the temporal lobe (s), with …

[HTML][HTML] Integrative Metabolomic Characterization Reveals the Mediating Effect of Bifidobacterium breve on Amino Acid Metabolism in a Mouse Model of Alzheimer's …

G Zhu, M Guo, J Zhao, H Zhang, G Wang, W Chen - Nutrients, 2022 - mdpi.com
Alzheimer's disease (AD) is commonly accompanied by global alterations in metabolic
profiles, resulting in cognitive impairment and neuroinflammation in the brain. Using …

Genetically encoded fluorescent sensors for imaging neuronal dynamics in vivo

J Day‐Cooney, R Dalangin, H Zhong… - Journal of …, 2023 - Wiley Online Library
The brain relies on many forms of dynamic activities in individual neurons, from synaptic
transmission to electrical activity and intracellular signaling events. Monitoring these …