[HTML][HTML] A historical review of brain drug delivery
WM Pardridge - Pharmaceutics, 2022 - mdpi.com
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …
[HTML][HTML] Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
[HTML][HTML] Road to the red carpet of edible crickets through integration into the human food chain with biofunctions and sustainability: A review
V Kemsawasd, W Inthachat, U Suttisansanee… - International journal of …, 2022 - mdpi.com
The Food and Agriculture Organization of the United Nations (FAO) estimates that more than
500 million people, especially in Asia and Africa, are suffering from malnutrition. Recently …
500 million people, especially in Asia and Africa, are suffering from malnutrition. Recently …
[HTML][HTML] Is it time to reconsider the US recommendations for dietary protein and amino acid intake?
M Weiler, SR Hertzler, S Dvoretskiy - Nutrients, 2023 - mdpi.com
Since the US Institute of Medicine's recommendations on protein and amino acid intake in
2005, new information supports the need to re-evaluate these recommendations. New lines …
2005, new information supports the need to re-evaluate these recommendations. New lines …
Advanced theragnostics for the central nervous system (CNS) and neurological disorders using functional inorganic nanomaterials
B Conklin, BM Conley, Y Hou, M Chen… - Advanced Drug Delivery …, 2023 - Elsevier
Various types of inorganic nanomaterials are capable of diagnostic biomarker detection and
the therapeutic delivery of a disease or inflammatory modulating agent. Those multi …
the therapeutic delivery of a disease or inflammatory modulating agent. Those multi …
[HTML][HTML] Nutrition, epigenetics, and major depressive disorder: understanding the connection
MA Ortega, Ó Fraile-Martínez, C García-Montero… - Frontiers in …, 2022 - frontiersin.org
Major Depressive Disorder (MDD) entails a multifactorial disorder of rising prevalence.
Nearly 280 million people suffer from this leading cause of disability in the world. Moreover …
Nearly 280 million people suffer from this leading cause of disability in the world. Moreover …
Recent advances in colorimetric and fluorometric sensing of neurotransmitters by organic scaffolds
M Chemchem, A Chemchem, B Aydıner… - European Journal of …, 2022 - Elsevier
Neurotransmitters are chemical compounds released by neurons acting as messengers that
transmit signals to other neurons, called postsynaptic neurons, or other types of cells. These …
transmit signals to other neurons, called postsynaptic neurons, or other types of cells. These …
[HTML][HTML] Synaptic reshaping and neuronal outcomes in the temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is one of the most common types of focal epilepsy,
characterized by recurrent spontaneous seizures originating in the temporal lobe (s), with …
characterized by recurrent spontaneous seizures originating in the temporal lobe (s), with …
[HTML][HTML] Integrative Metabolomic Characterization Reveals the Mediating Effect of Bifidobacterium breve on Amino Acid Metabolism in a Mouse Model of Alzheimer's …
G Zhu, M Guo, J Zhao, H Zhang, G Wang, W Chen - Nutrients, 2022 - mdpi.com
Alzheimer's disease (AD) is commonly accompanied by global alterations in metabolic
profiles, resulting in cognitive impairment and neuroinflammation in the brain. Using …
profiles, resulting in cognitive impairment and neuroinflammation in the brain. Using …
Genetically encoded fluorescent sensors for imaging neuronal dynamics in vivo
J Day‐Cooney, R Dalangin, H Zhong… - Journal of …, 2023 - Wiley Online Library
The brain relies on many forms of dynamic activities in individual neurons, from synaptic
transmission to electrical activity and intracellular signaling events. Monitoring these …
transmission to electrical activity and intracellular signaling events. Monitoring these …