Principles of antibody-mediated TNF receptor activation
H Wajant - Cell Death & Differentiation, 2015 - nature.com
From the beginning of research on receptors of the tumor necrosis factor (TNF) receptor
superfamily (TNFRSF), agonistic antibodies have been used to stimulate TNFRSF receptors …
superfamily (TNFRSF), agonistic antibodies have been used to stimulate TNFRSF receptors …
[PDF][PDF] In-vacuum long-wavelength macromolecular crystallography
A Wagner, R Duman, K Henderson… - … Section D: Structural …, 2016 - journals.iucr.org
Structure solution based on the weak anomalous signal from native (protein and DNA)
crystals is increasingly being attempted as part of synchrotron experiments. Maximizing the …
crystals is increasingly being attempted as part of synchrotron experiments. Maximizing the …
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage
Asparaginyl endopeptidase (AEP) is an endo/lysosomal cysteine endopeptidase with a
preference for an asparagine residue at the P1 site and plays an important role in the …
preference for an asparagine residue at the P1 site and plays an important role in the …
Structural and biochemical characterization reveals LysGH15 as an unprecedented “EF-hand-like” calcium-binding phage lysin
J Gu, Y Feng, X Feng, C Sun, L Lei, W Ding… - PLoS …, 2014 - journals.plos.org
The lysin LysGH15, which is derived from the staphylococcal phage GH15, demonstrates a
wide lytic spectrum and strong lytic activity against methicillin-resistant Staphylococcus …
wide lytic spectrum and strong lytic activity against methicillin-resistant Staphylococcus …
Combination therapy of LysGH15 and apigenin as a new strategy for treating pneumonia caused by Staphylococcus aureus
F Xia, X Li, B Wang, P Gong, F Xiao… - Applied and …, 2016 - Am Soc Microbiol
Pneumonia is one of the most prevalent Staphylococcus aureus-mediated diseases, and the
treatment of this infection is becoming challenging due to the emergence of multidrug …
treatment of this infection is becoming challenging due to the emergence of multidrug …
Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling
4-1BB (CD137) is a TNF receptor superfamily (TNFRSF) member that is thought to undergo
receptor trimerization upon binding to its trimeric TNF superfamily ligand (4-1BBL) to …
receptor trimerization upon binding to its trimeric TNF superfamily ligand (4-1BBL) to …
Structure of the Leanyer orthobunyavirus nucleoprotein–RNA complex reveals unique architecture for RNA encapsidation
Negative-stranded RNA viruses cover their genome with nucleoprotein (N) to protect it from
the human innate immune system. Abrogation of the function of N offers a unique …
the human innate immune system. Abrogation of the function of N offers a unique …
[PDF][PDF] Long-wavelength native-SAD phasing: opportunities and challenges
Native single-wavelength anomalous dispersion (SAD) is an attractive experimental phasing
technique as it exploits weak anomalous signals from intrinsic light scatterers (Z< 20). The …
technique as it exploits weak anomalous signals from intrinsic light scatterers (Z< 20). The …
TNFRSF21 mutations cause high myopia
H Pan, S Wu, J Wang, T Zhu, T Li, B Wan… - Journal of Medical …, 2019 - jmg.bmj.com
Background High myopia (HM) is one of the leading causes of vision impairment worldwide,
accompanied by a series of pathological ocular complications. Studies have shown that …
accompanied by a series of pathological ocular complications. Studies have shown that …