Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Cough peak flow (CPF) is a useful clinical measurement to assess neuromuscular activity
and effective coordination, yet it is rarely used in clinical practice outside of the management …

Neuroinflammation is involved in the pathogenesis of amyotrophic lateral sclerosis (ALS),
but only limited data are available on systematic peripheral and central immune cell profiles …

Background Respiratory failure is a significant concern in neuromuscular diseases (NMDs).
This CHEST guideline examines the literature on the respiratory management of patients …

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease inevitably leading
to generalized muscle weakness and premature death. Sleep disturbances are extremely …

Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
characterized by progressive diaphragm weakness and deteriorating lung function. Bulbar …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper
and lower motor neuron death. Involvement of respiratory motor neuron pools leads to …

Objective This retrospective study aimed to investigate whether overnight oxymetry and
early morning blood gas analysis predict nocturnal hypoventilation (NH) as reflected by …

Objective: Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease that
causes skeletal muscle weakness, including muscles involved with respiration. Death often …

Abstract Purpose of Review In amyotrophic lateral sclerosis (ALS), sleep disruption is
frequently present and substantially adds to disease burden. This review aims to summarize …