Despite extensive evidence showing that exposure to specific chemicals can lead to
disease, current research approaches and regulatory policies fail to address the chemical …

The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …

Objective To summarize the application of non-targeted metabolomics in epidemiological
studies that assessed metabolite and metabolic pathway alterations associated with per-and …

Background: Exposure to per-and polyfluoroalkyl substances (PFAS) is ubiquitous and has
been associated with an increased risk of several cardiometabolic diseases. However, the …

Abstract Per and Polyfluoroalkyl Substances (PFAS) are a diverse group of man-made
chemicals with a range of industrial applications and which are widespread in the …

Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …

The exposome concept encourages holistic consideration of the non-genetic factors
(environmental exposures including lifestyle) that influence an individual's health over their …

Abstract Purpose of Review There is a growing interest in understanding the health effects of
exposure to per-and polyfluoroalkyl substances (PFAS) through the study of the human …

Breast cancer is now the most common cancer globally, accounting for 12% of all new
annual cancer cases worldwide. Despite epidemiologic studies having established a …

Benzene is a recognized hematotoxin and leukemogen; however, its mechanism of action in
humans remain unclear. To provide insight into the processes underlying benzene …