Maladaptive plasticity in tinnitus—triggers, mechanisms and treatment
Tinnitus is a phantom auditory sensation that reduces quality of life for millions of people
worldwide, and for which there is no medical cure. Most cases of tinnitus are associated with …
worldwide, and for which there is no medical cure. Most cases of tinnitus are associated with …
[HTML][HTML] Mechanisms of noise-induced tinnitus: insights from cellular studies
Tinnitus, sound perception in the absence of physical stimuli, occurs in 15% of the
population and is the top-reported disability for soldiers after combat. Noise overexposure is …
population and is the top-reported disability for soldiers after combat. Noise overexposure is …
Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans
The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian
auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve …
auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve …
Reversing synchronized brain circuits using targeted auditory-somatosensory stimulation to treat phantom percepts: a randomized clinical trial
Importance Animal models have shown altered dorsal cochlear nucleus circuitry in animals
that develop tinnitus; however, precise treatment using bisensory (auditory and …
that develop tinnitus; however, precise treatment using bisensory (auditory and …
Glutamatergic projections to the cochlear nucleus are redistributed in tinnitus
Tinnitus alters auditory–somatosensory plasticity in the cochlear nucleus (CN).
Correspondingly, bimodal auditory–somatosensory stimulation treatment attenuates tinnitus …
Correspondingly, bimodal auditory–somatosensory stimulation treatment attenuates tinnitus …
[HTML][HTML] The pathological mechanisms and treatments of tinnitus
S Saeed, QU Khan - Discoveries, 2021 - ncbi.nlm.nih.gov
Tinnitus is defined as the ringing, hissing, clicking or roaring sounds an individual
consciously perceives in the absence of an external auditory stimulus. Currently, the …
consciously perceives in the absence of an external auditory stimulus. Currently, the …
Hebbian spike-timing dependent plasticity at the cerebellar input stage
Spike-timing-dependent plasticity (STDP) is a form of long-term synaptic plasticity exploiting
the time relationship between postsynaptic action potentials (APs) and EPSPs. Surprisingly …
the time relationship between postsynaptic action potentials (APs) and EPSPs. Surprisingly …
An update: emerging drugs for tinnitus
CR Cederroth, J Dyhrfjeld-Johnsen… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: During the last decade, a number of candidate drugs for the treatment of
tinnitus have emerged with the hope of alleviating the burden of millions of sufferers with a …
tinnitus have emerged with the hope of alleviating the burden of millions of sufferers with a …
[HTML][HTML] Integrative treatment for tinnitus combining repeated facial and auriculotemporal nerve blocks with stimulation of auditory and non-auditory nerves
SJ Sirh, SW Sirh, HY Mun, HM Sirh - Frontiers in Neuroscience, 2022 - frontiersin.org
Background Tinnitus is a prevalent condition (> 10% of the population) affecting the quality
of life of 0.5–3% of the population. Although several treatments have been proposed, most of …
of life of 0.5–3% of the population. Although several treatments have been proposed, most of …
[HTML][HTML] An investigation of feasibility and safety of bi-modal stimulation for the treatment of tinnitus: an open-label pilot study
C Hamilton, S D'Arcy, BA Pearlmutter… - … : Technology at the …, 2016 - Elsevier
Objectives Tinnitus is the perception of sound in the absence of an external auditory
stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a …
stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a …