Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

abstract Atopic dermatitis (AD) is a heterogenous disorder and can be classified into
different types. Stratification of subtypes may enable personalized medicine approaches. AD …

Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

Postulated by Strachan more than 30 years ago, the Hygiene Hypothesis has undergone
many revisions and adaptations. This review journeys back to the beginnings of the Hygiene …

The role of the gut microbiota in human health and disease has garnered heightened
attention over the past decade. A thorough understanding of microbial variation over the life …

Microfluidic technologies have been extensively investigated in recent years for developing
organ-on-a-chip-devices as robust in vitro models aiming to recapitulate organ 3D …

A healthy indigenous intestinal microbiome is indispensable for intra-and extra-intestinal
human health. Since well-established factors such as diet and antibiotic use only explain …

Asthma and other allergic disorders, such as atopic dermatitis and food allergies, are
common chronic health problems in childhood. The rapid rise in the prevalence of these …

Celastrol, a quinone‐methide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …

In recent years, the role of human microbiota as a short-and long-term health promoter and
modulator has been affirmed and progressively strengthened. In the course of one's life …