Melanoma management: from epidemiology to treatment and latest advances

J Lopes, CMP Rodrigues, MM Gaspar, CP Reis - Cancers, 2022 - mdpi.com
Simple Summary Melanoma is a major public health issue that claims the lives of thousands
of people every year. Furthermore, the outlook for the coming years is not encouraging with …

[HTML][HTML] Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures

NH Khan, M Mir, L Qian, M Baloch, MFA Khan… - Journal of Advanced …, 2022 - Elsevier
Background Skin cancer has been the leading type of cancer worldwide. Melanoma and
non-melanoma skin cancers are now the most common types of skin cancer that have been …

[HTML][HTML] ESMO consensus conference recommendations on the management of locoregional melanoma: under the auspices of the ESMO Guidelines Committee

O Michielin, A Van Akkooi, P Lorigan, PA Ascierto… - Annals of …, 2020 - Elsevier
Highlights•A melanoma consensus conference, organised by the ESMO Guidelines
Committee, was attended by 32 experts from 14 countries•The experts compiled …

Melanoma development: current knowledge on melanoma pathogenesis

P Vuković, L Lugović-Mihić, D Ćesić… - Acta …, 2019 - hrcak.srce.hr
Sažetak The pathogenic features of melanomas include growth and amplification of atypical
melanocytes associated with several features (self-sufficiency of growth factors, insensitivity …

[HTML][HTML] Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I: C) promote melanoma regression

Z Zhang, Y Xue, G Wang, Y Cheng, Y Pan, S Zhao… - Theranostics, 2018 - ncbi.nlm.nih.gov
Macrophages orchestrate inflammation and control the promotion or inhibition of tumors and
metastasis. Ferumoxytol (FMT), a clinically approved iron oxide nanoparticle, possesses anti …

The challenging melanoma landscape: From early drug discovery to clinical approval

M Matias, JO Pinho, MJ Penetra, G Campos, CP Reis… - Cells, 2021 - mdpi.com
Melanoma is recognized as the most dangerous type of skin cancer, with high mortality and
resistance to currently used treatments. To overcome the limitations of the available …

How to treat melanoma? the current status of innovative nanotechnological strategies and the role of minimally invasive approaches like PTT and PDT

J Lopes, CMP Rodrigues, MM Gaspar, CP Reis - Pharmaceutics, 2022 - mdpi.com
Melanoma is the most aggressive type of skin cancer, the incidence and mortality of which
are increasing worldwide. Its extensive degree of heterogeneity has limited its response to …

Assessment of betulinic acid cytotoxicity and mitochondrial metabolism impairment in a human melanoma cell line

D Coricovac, CA Dehelean, I Pinzaru, A Mioc… - International Journal of …, 2021 - mdpi.com
Melanoma represents one of the most aggressive and drug resistant skin cancers with poor
prognosis in its advanced stages. Despite the increasing number of targeted therapies …

A four-DNA methylation biomarker is a superior predictor of survival of patients with cutaneous melanoma

W Guo, L Zhu, R Zhu, Q Chen, Q Wang, JQ Chen - Elife, 2019 - elifesciences.org
Cutaneous melanoma (CM) is a life-threatening form of skin cancer. Prognostic biomarkers
can reliably stratify patients at initial melanoma diagnosis according to risk, and may inform …

Exosomes in chronic inflammatory skin diseases and skin tumors

WM Wang, C Wu, HZ Jin - Experimental dermatology, 2019 - Wiley Online Library
Exosomes are membrane vesicles of endocytic origin that can mediate communication
between cells and the transport of cellular components such as microRNAs, mRNAs …