Spanning functions from the simplest reflex arc to complex cognitive processes, neural
circuits have diverse functional roles. In the cerebral cortex, functional domains such as …

Enormous progress has been made in assessing the neonatal brain, using magnetic
resonance imaging (MRI). In this review, we will describe the use of MRI and proton …

OBJECTIVE: To review the maturational events that occur during prenatal and postnatal
brain development and to present neuroimaging findings from studies of healthy individuals …

Hypoxic-ischemic encephalopathy (HIE) is a major cause of neurological sequelae in (near-
) term newborns. Despite the use of therapeutic hypothermia, a significant number of …

Regional changes of metabolite concentrations during human brain development were
assessed by quantitative localized proton magnetic resonance spectroscopy in vivo. Apart …

Biochemical maturation of the brain can be studied noninvasively by 1H magnetic
resonance spectroscopy (MRS) in human infants. Detailed time courses of cerebral tissue …

Volumetric proton magnetic resonance spectroscopic imaging (MRSI) was used to generate
brain metabolite maps in 15 young and 19 elderly adult volunteers. All subjects also had …

Between birth and late adolescence, the human brain undergoes exponential maturational
changes. Using in vivo magnetic resonance spectroscopy, we determined the …

BACKGROUND AND PURPOSE: Neurologic and developmental outcomes of asphyxiated,
term neonates are difficult to predict applying clinical or laboratory criteria. In this study, we …

Magnetic resonance spectroscopy (MRS) provides a noninvasive means of assessing in
vivo tissue biochemistry. N‐Acetyl aspartate (NAA) is a major brain metabolite, and its …