Review and Theoretical Analysis of Fluorinated Radicals in Direct CAr−H Functionalization of (Hetero)arenes

AJ Fernandes, R Giri, KN Houk… - Angewandte Chemie, 2024 - Wiley Online Library
We highlight key contributions in the field of direct radical CAr− H (hetero) aromatic
functionalization involving fluorinated radicals. A compilation of Functional Group Transfer …

Building Catalytic Reactions One Electron at a Time

JG West - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus Classical education in organic chemistry and catalysis, not the least my own,
has centered on two-electron transformations, from nucleophilic attack to oxidative addition …

Direct Benzylic C− H Etherification Enabled by Base‐Promoted Halogen Transfer

KI Bone, TR Puleo, MD Delost, Y Shimizu… - Angewandte …, 2024 - Wiley Online Library
We disclose a benzylic C− H oxidative coupling reaction with alcohols that proceeds through
a synergistic deprotonation, halogenation and substitution sequence. The combination of …

Basicity of MnIII-Hydroxo Complexes Controls the Thermodynamics of Proton-Coupled Electron Transfer Reactions

P Singh, MJA Lomax, AA Opalade, BB Nguyen… - Inorganic …, 2024 - ACS Publications
Several manganese-dependent enzymes utilize MnIII-hydroxo units in concerted proton–
electron transfer (CPET) reactions. We recently demonstrated that hydrogen bonding to the …

Repurposing quantum chemical descriptor datasets for on-the-fly generation of informative reaction representations: application to hydrogen atom transfer reactions

JE Alfonso-Ramos, RM Neeser, T Stuyver - Digital Discovery, 2024 - pubs.rsc.org
In this work, we explore how existing datasets of quantum chemical properties can be
repurposed to build data-efficient downstream machine learning models, with a particular …

Tuning Energetics of 2 e/2H+ PCET Properties with Model Ru‐bisamido Complexes

M Cattaneo, ET Gallmeier, PO Abate… - … A European Journal, 2024 - Wiley Online Library
Most redox processes that break/form bonds involve net 2e− changes, and many are
coupled to protons. Yet most proton‐coupled electron transfer (PCET) studies focus on …

[PDF][PDF] DIFFERENT BIOLOGICAL ACTIVITIES AND STRUCTURE ACTIVITY STUDIES OF ACRIDINE AND ACRIDONE DERIVATIVES: AN UPDATED REVIEW

S Nandi, S Bhunia, I Debnath, S Hazra, S Ghosh… - 2024 - researchgate.net
Acridine and its derivatives' diverse biological functions are thoroughly and up-to-date
analyzed in this review, focusing on the structure-activity relationship (SAR) between them …

[图书][B] Experimental and Theoretical Evidence for Diverse Thermodynamic Influences on Transition Metal-Oxo Mediated C–H Activation

JE Schneider - 2024 - search.proquest.com
The selective activation and functionalization of C–H bonds is a major challenge in synthetic
chemistry. Transition metal-oxo complexes are particularly adept at accomplishing such …

Role of Noncovalent Interactions in The Reaction of Bromine with Alkylacetamides

OM Zarechnaya, VA Mikhailov - Žurnal obŝej himii, 2024 - journals.rcsi.science
Sequential transformations of molecular complexes and ionic intermediates lead to ionic
products of nonionic bromine and alkylacetamides interaction. Molecular geometry, electron …